Clinical Correlations in Hiv-1 and Hiv-2 Infected Patients

Autor: Neves C, Galvao J, Monteiro-Grillo M, Ribeiro-da-Silva J, Sousa Ap, Yueh M
Rok vydání: 1993
Předmět:
Zdroj: CIÊNCIAVITAE
Scopus-Elsevier
ISSN: 1724-6016
1120-6721
DOI: 10.1177/112067219300300103
Popis: In Portugal, the prevalence of human immunodeficiency virus type 2 (HIV-2) seropositivity is higher than in other European countries or North America. Recent literature data points out a possible difference on the pathogenic potential and on the natural history of HIV-1 and HIV-2, suggesting a lower virulence of HIV-2. Facing these hypothesis and the increasing number of HIV-2 cases, we analysed two infected groups HIV-1 and HIV-2, trying to correlate the ophthalmologic lesions present in both populations and searching for a difference in the clinical presentation of the ocular disorder. We studied prospectively 214 patients with HIV infection at several stages, 83% HIV-1 and 17% HIV-2. Ocular manifestations were present in both populations with a significant prevalence in HIV-1 (48%), compared to HIV-2 (19%) (p
Databáze: OpenAIRE