Effects of chair-restraint on gastrointestinal transit time and colonic fermentation in male rhesus monkey (Macaca mulatta)
| Autor: | Sylvie Rabot, Martine Bensaada, Françoise Popot, Odette Szylit, Michel Viso, Franck Martin, Jean-Pierre Blanquie, Nancy D. Searby, P. Vaissade |
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| Přispěvatelé: | Unité de recherche d'Écologie et Physiologie du Système Digestif (UEPSD), Institut National de la Recherche Agronomique (INRA), ProdInra, Migration |
| Jazyk: | angličtina |
| Rok vydání: | 1997 |
| Předmět: |
Male
Restraint Physical medicine.medical_specialty rhesus Colon Gastrointestinal transit time [SDV]Life Sciences [q-bio] ACIDE GRAS A COURTE CHAINE Feces Ammonia Internal medicine biology.animal medicine Colonic fermentation Animals Dry matter Primate Gastrointestinal Transit General Veterinary biology AGV Dietary composition Mean value Fatty Acids Hydrogen-Ion Concentration Macaca mulatta Digestive physiology [SDV] Life Sciences [q-bio] Endocrinology Fermentation Animal Science and Zoology Biomarkers |
| Zdroj: | Journal of Medical Primatology Journal of Medical Primatology, Wiley, 1997, 26 (4), pp.190-195 |
| ISSN: | 0047-2565 1600-0684 |
| Popis: | The incidence of an 18 day chair-restraint on the digestive physiology of male rhesus monkey was investigated for space research purposes, comparing four trained restraint subjects with two vivarium controls. Chair-restraint induced a 2.5-fold acceleration of the gastrointestinal transit time, which persisted throughout the 7 day postrestraint period, and an increase of the fecal dry matter content, which mean value rose from 40.7% to 69.6%. Fecal pH remained unaltered throughout the experiment. Modifications of fermentative metabolites produced by the colonic microflora and excreted through the breath (hydrogen and methane) or in the feces (short chain fatty acids and ammonia) could not be reliably related to chair-restraint and probably involved side-stress factors. On the whole, alterations due to chair-restraint are shown to be different from those reported in the literature, following a modification of the dietary composition. These data may help to predict the alterations of digestive physiology likely to occur in immobilized human patients. |
| Databáze: | OpenAIRE |
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