Use of sustainable chemistry to produce an acyl amino acid surfactant
| Autor: | Prashanth Vishwanath, Jeffrey J. Todd, Ponisseril Somasundaran, Michelle A. Pynn, Kevin A. Jarrell, Gabriel Reznik, Brendan G. Keenan, Joy M. Sitnik, Jun Wu, Yan Jiang, Richard F. Haskell, Andrew B. Castle, Temple F. Smith |
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| Rok vydání: | 2010 |
| Předmět: |
Green chemistry
Molecular Sequence Data Glutamic Acid Foaming agent Raw material Protein Engineering Peptides Cyclic Applied Microbiology and Biotechnology Dispersant Lipopeptides Surface-Active Agents chemistry.chemical_compound Bacterial Proteins Pulmonary surfactant Nonribosomal peptide Organic chemistry Amino Acid Sequence Peptide Synthases Cellulose Micelles chemistry.chemical_classification General Medicine Solubility chemistry Fermentation lipids (amino acids peptides and proteins) Surfactin Bacillus subtilis Biotechnology |
| Zdroj: | Applied Microbiology and Biotechnology. 86:1387-1397 |
| ISSN: | 1432-0614 0175-7598 |
| Popis: | Surfactants find wide commercial use as foaming agents, emulsifiers, and dispersants. Currently, surfactants are produced from petroleum, or from seed oils such as palm or coconut oil. Due to concerns with CO(2) emissions and the need to protect rainforests, there is a growing necessity to manufacture these chemicals using sustainable resources In this report, we describe the engineering of a native nonribosomal peptide synthetase pathway (i.e., surfactin synthetase), to generate a Bacillus strain that synthesizes a highly water-soluble acyl amino acid surfactant, rather than the water insoluble lipopeptide surfactin. This novel product has a lower CMC and higher water solubility than myristoyl glutamate, a commercial surfactant. This surfactant is produced by fermentation of cellulosic carbohydrate as feedstock. This method of surfactant production provides an approach to sustainable manufacturing of new surfactants. |
| Databáze: | OpenAIRE |
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