Clinical characteristics of female patients with coronary spastic angina: comparison with male patients
| Autor: | Hiroyuki Kawada, Kazuo Yano, Jun Suzuki, Shozo Sueda, Shouzou Matsuda, Kazuaki Mineoi, Hitoshi Kukita, Kouki Watanabe, Tadao Uraoka, Yutaka Hayashi, Takashi Tsuruoka, Naoto Ochi, Tadashi Kondou, Takaaki Ochi |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Angina Pectoris
Variant Male medicine.medical_specialty Physiology Provocation test Angina Left coronary artery Sex Factors medicine.artery Internal medicine medicine Spastic Humans cardiovascular diseases Aged business.industry Vasospasm Middle Aged medicine.disease Stenosis Right coronary artery Cardiology Ergonovine Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Japanese circulation journal. 64(6) |
| ISSN: | 0047-1828 |
| Popis: | There are many patients with vasospastic angina who have minor atherosclerosis, and in Japan the majority of them are male. No data exist concerning sex differences in patients with coronary spastic angina, so the present study sought to clarify the clinical characteristics between male and female patients with vasospastic angina. Between April 1991 and June 1998, 204 consecutive patients were diagnosed with vasospastic angina and of these, 26 (12.7%) were female. An acetylcholine test was performed with incremental doses of 20, 50, and 80 microg injected into the right coronary artery and 20, 50, and 100 microg into the left coronary artery. Ergonovine was injected in a total dose of 40 microg into the right coronary artery and 64 microg into the left coronary artery. Coronary spasm was defined as 99% or more luminal narrowing accompanied by ischemic changes on ECG. Compared with male patients, female patients had less organic stenosis (12 vs 33%, p |
| Databáze: | OpenAIRE |
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