Role of environmental factors in shaping spatial distribution of salmonella enterica Serovar Typhi, Fiji

Autor: Nga Tran Vu Thieu, Kitione Rawalai, Tan Trinh Van, Jerimaia Coriakula, Colleen L. Lau, Conall H. Watson, Jorge Cano, Ruklanthi de Alwis, Mere Taufa, Mike Kama, Birgit Nikolay, Stephen Baker, John H. Lowry, W. John Edmunds, Dung Tran Thi Ngoc, Eric J. Nilles
Přispěvatelé: Baker, Stephen [0000-0003-1308-5755], Apollo - University of Cambridge Repository
Předmět:
Veterinary medicine
Epidemiology
Cross-sectional study
lcsh:Medicine
Salmonella typhi
Serology
0302 clinical medicine
Seroepidemiologic Studies
Environmental Microbiology
Cluster Analysis
risk factors
030212 general & internal medicine
Child
bacteria
Aged
80 and over
seroprevalence
Middle Aged
Antibodies
Bacterial
3. Good health
Vaccination
Infectious Diseases
Child
Preschool
Salmonella enterica serovar Typhi
multilevel analysis
typhoid fever
Microbiology (medical)
Adult
Adolescent
030231 tropical medicine
Vi antibodies
Biology
Disease cluster
Peptides
Cyclic
Typhoid fever
Role of Environmental Factors in Shaping Spatial Distribution of Salmonella enterica Serovar Typhi
Fiji
lcsh:Infectious and parasitic diseases
03 medical and health sciences
flooding
environmental factors
medicine
Seroprevalence
Fiji
Humans
lcsh:RC109-216
Aged
Research
lcsh:R
Infant
Newborn
Infant
Odds ratio
medicine.disease
Cross-Sectional Studies
Vi capsular antigen
Zdroj: Emerging Infectious Diseases, Vol 24, Iss 2, Pp 284-293 (2018)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
Popis: Fiji recently experienced a sharp increase in reported typhoid fever cases. To investigate geographic distribution and environmental risk factors associated with Salmonella enterica serovar Typhi infection, we conducted a cross-sectional cluster survey with associated serologic testing for Vi capsular antigen-specific antibodies (a marker for exposure to Salmonella Typhi in Fiji in 2013. Hotspots with high seroprevalence of Vi-specific antibodies were identified in northeastern mainland Fiji. Risk for Vi seropositivity increased with increased annual rainfall (odds ratio [OR] 1.26/quintile increase, 95% CI 1.12-1.42), and decreased with increased distance from major rivers and creeks (OR 0.89/km increase, 95% CI 0.80-0.99) and distance to modeled flood-risk areas (OR 0.80/quintile increase, 95% CI 0.69-0.92) after being adjusted for age, typhoid fever vaccination, and home toilet type. Risk for exposure to Salmonella Typhi and its spatial distribution in Fiji are driven by environmental factors. Our findings can directly affect typhoid fever control efforts in Fiji.
Databáze: OpenAIRE
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