Characteristics and management of congenital anophthalmos and microphthalmos at a tertiary eye hospital
| Autor: | Saif Aldossari, Silvana Artioli Schellini, Patricia Akaishi, Laila AlGhafri, Fatimah Alhammad, Alicia Galindo-Ferreiro, Osama AlShaikh, Dalal Alessa, Manar AlWehaib, Sahar M. Elkhamary, Rajiv Khadekar |
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| Přispěvatelé: | Rio Hortega University Hospital, King Khaled Eye Specialist Hospital, Mansoura Faculty Of Medicine, Universidade de São Paulo (USP), Universidade Estadual Paulista (Unesp) |
| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Adolescent medicine.medical_treatment Enucleation Visual Acuity Microphthalmia Prosthesis Eye Enucleation Surgical Flaps Prosthesis Implantation Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Patient age Anophthalmos medicine Humans Microphthalmos Anophthalmia disorders Evisceration (ophthalmology) Retrospective Studies Eye Artificial business.industry congenital medicine.disease eye diseases Surgery Ophthalmology Cross-Sectional Studies 030104 developmental biology microphthalmia outcome 030221 ophthalmology & optometry Female Tomography X-Ray Computed business Eye Evisceration Orbital Implants |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 1744-5108 0167-6830 |
| Popis: | Made available in DSpace on 2019-10-06T16:52:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-05-04 Purpose: The purpose of the study is to evaluate demographic data and outcomes of the management of congenital anophthalmia/microphthalmia. Methods: This retrospective, descriptive, cross-sectional study evaluated patients with congenital anophthalmia/microphthalmia managed from 2004 to 2014 at a tertiary hospital in Saudi Arabia. Data were collected on patient age, gender, cause, orbital status, laterality, systemic comorbidities, ocular evaluation, and management (type of surgery, type of orbital implant, and complications). The main outcome measure was the ability to hold the prosthesis. Results: The study sample was composed of 513 eyes/sockets of 365 patients. Two-hundred and seventeen (59.4%) patients were unilateral cases. Forty-one (8%) sockets were due to congenital anophthalmia and 471 (92%) were due to microphthalmia. There were 73.2% isolated cases and 28.5% with systemic involvement. Systemic involvement was more common in bilateral cases. The most commonly associated conditions were central nervous disorders. One-hundred and nineteen (46.7%) cases had parental consanguinity. Two hundred and eighteen eyes/sockets (163 patients) underwent surgery including conjunctival flap (38; 17.4%), evisceration (38; 17.4%), enucleation (16; 7.3%), or procedures to improve the anophthalmic socket volume (45; 20.6%). Volume enhancing procedures included polymethylmethacrylate orbital implants (26; 57.8%), expanders (11; 24.4%), integrated hydroxyapatite or polyethylene implants (2; 4.4%), and dermis-fat graft (6; 13.3%). In most cases, clinical or surgical management resulted in a successful outcome. Conclusion: Anophthalmia/Microphthalmia was detected in 36.5 patients/year. The majority had isolated microphthalmia. Good outcomes were achieved with clinical or surgical management in the majority of cases. Department of Ophthalmology Rio Hortega University Hospital Oculoplastics and Orbit Division King Khaled Eye Specialist Hospital Diagnostic Imaging Department King Khaled Eye Specialist Hospital Diagnostic Imaging Department Mansoura Faculty Of Medicine Department of Ophthalmology Faculdade de Medicina da Universidade de São Paulo–USP- Ribeirao Preto Department of Ophthalmology Faculdade de Medicina - Universidade Estadual Paulista - UNESP Department of Ophthalmology Faculdade de Medicina - Universidade Estadual Paulista - UNESP |
| Databáze: | OpenAIRE |
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