Effect of Acetazolamide on the Insulin Response to Intravenous Administration of Secretin
| Autor: | Sotirios Raptis, H.C. Dollinger, G. Rothenbuchner, E. F. Pfeiffer, U. Klör, R. Fussgänger |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Blood Glucose
Glycerol medicine.medical_specialty Duodenum medicine.medical_treatment Bicarbonate Medicine (miscellaneous) Fatty Acids Nonesterified Secretin Islets of Langerhans chemistry.chemical_compound Duodenal juice Pancreatic Juice Internal medicine Insulin Secretion Insulin response Humans Insulin Medicine Antigens Insulin secretion Pancreas Nutrition and Dietetics Intestinal Secretions business.industry Pancreatic Diseases Drug Synergism Acetazolamide Bicarbonates Endocrinology Inhalation chemistry Exocrine pancreas Chronic Disease Injections Intravenous business medicine.drug |
| Zdroj: | Annals of Nutrition and Metabolism. 16:79-86 |
| ISSN: | 1421-9697 0250-6807 |
| DOI: | 10.1159/000175475 |
| Popis: | In 15 subjects, secretin administered intravenously increased the insulin secretion significantly as well as volume and bicarbonate content of the duodenal juice. The inhibition of the exocrine pancreas by acetazolamide did not influence the β-cytotropic effect of secretin. The loss of this effect in patients suffering from chronic pancreatic insufficiency seems, therefore, to be caused, not by the decreased volume and bicarbonate secretion, butby other unknown factors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|