Long-term survival of a patient with stage IIIC2 grade 3 endometrioid endometrial carcinoma treated with surgery alone
| Autor: | Takuto Matsuura, Mizuho Kadooka, Isao Otsuka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Endometrial cancer Long term survival Carcinoma medicine Case Reports and Case Series Pelvic node Stage (cooking) Pathological RC254-282 Chemotherapy business.industry Neoplasms. Tumors. Oncology. Including cancer and carcinogens Obstetrics and Gynecology Lymphadenectomy Gynecology and obstetrics medicine.disease Surgery Grade 3 endometrioid carcinoma Para-aortic lymph node metastasis Oncology RG1-991 Abnormality business |
| Zdroj: | Gynecologic Oncology Reports Gynecologic Oncology Reports, Vol 38, Iss, Pp 100869-(2021) |
| ISSN: | 2352-5789 |
| Popis: | Highlights • The therapeutic benefit of lymphadenectomy in endometrial carcinoma is controversial. • Long-term survival was achieved in a stage IIIC2 patient treated with surgery alone. • Pelvic and para-aortic lymphadenectomy may have a therapeutic benefit. Background The therapeutic benefit of lymphadenectomy in endometrial carcinoma is controversial. Case A 70-year-old woman with grade 3 endometrioid endometrial carcinoma with deep myometrial invasion underwent surgical staging comprising total abdominal hysterectomy, bilateral salpingo-oophorectomy, peritoneal cytology, and pelvic and para-aortic lymphadenectomy. Pathological examination revealed micro-metastases in the para-aortic node, pelvic node, and left ovary. Peritoneal cytology was negative, and abnormal p53 expression was not detected. The patient was diagnosed with stage IIIC2 endometrial carcinoma. Adjuvant chemotherapy was advised, but the patient refused chemotherapy and was followed up regularly thereafter. The patient survived without any evidence of disease 67 months after surgery. Conclusion Pelvic and para-aortic lymphadenectomy may have a therapeutic benefit in a patient with high-grade endometrioid carcinoma, but without p53 abnormality. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|