| Autor: |
M, Ciprés, M, Satue, I, Melchor, L, Gil-Arribas, E, Vilades, E, Garcia-Martin |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Archivos de la Sociedad Española de Oftalmología (English Edition). 97:205-218 |
| ISSN: |
2173-5794 |
| Popis: |
In diabetes mellitus (DM) patients retinal complications were typically considered part of a vascular process. Recent research suggests that retinal degeneration in DM might also be caused by a neuropathy that could precede microvascular alterations. The present work reviews the currently available bibliography about neurodegeneration in patients with type 2 DM (DM2) without diabetic retinopathy (DR). In patients with non-severe, early DM2 without DR and good metabolic control visual function parameters show early abnormalities that precede clinical DR (in which we diagnose with a conventional ophthalmological examination). Using optical coherence tomography (OCT) technology, a reduction in macular and peripapillary thickness has been observed in different studies. Recent researches suggest that systemic complications (especially ischaemia) and a possible microvascular alteration eventually contributes to retinal neurodegeneration, which opens the door to new studies that include new techniques for evaluating the microvascularization of the retinal layers. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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