Rennies, Crohn's disease and severe hypercalcaemia
| Autor: | Filip Zemrak, Lisa McNeil, Norman Peden |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Hypercalcaemia Calcitriol chemistry.chemical_element Calcium Inflammatory bowel disease Gastroenterology Severity of Illness Index Article Calcium Carbonate Antacid Preparation Crohn Disease Internal medicine Severity of illness medicine Humans Magnesium Crohn's disease business.industry General Medicine Middle Aged medicine.disease Endocrinology chemistry Vomiting Hypercalcemia Female medicine.symptom business medicine.drug |
| Popis: | A 59-year-old lady presented with vomiting and diarrhoea. She was found to have severe hypercalcaemia (5.2 mmol/l) and to be in renal failure. She had a high daily intake of calcium carbonate in the form of Rennies Dual Action, raising the possibility of milk-alkali syndrome. She had ongoing gastrointestinal symptoms after resolution of hypercalcaemia. Further investigation revealed, previously undiagnosed rectal Crohn's disease. Serum 1,25-dihydroxyvitamin D (calcitriol) level was markedly elevated. It is possible that the calcitriol from Crohn's disease tissue facilitated excessive absorption of calcium from the antacid preparation, thus triggering hypercalcaemia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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