Histological verification of non-specific aorta-arteritis (Takayasu's arteritis) using percutaneous transluminal atherectomy
| Autor: | Chr. Müller, Uwe Schwarzwälder, P. Amantea, Karlheinz Bürgelin, Ulrich Frank, Florian Neumann, H. Koch, Tanja Zeller, Aljoscha Rastan |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Systemic disease medicine.medical_specialty Atherectomy Percutaneous Biopsy medicine.medical_treatment medicine.artery medicine Humans Arteritis Aorta Vascular disease business.industry Middle Aged medicine.disease Takayasu Arteritis Surgery Treatment Outcome medicine.anatomical_structure Female Radiology Cardiology and Cardiovascular Medicine business Vasculitis Artery |
| Zdroj: | Vasa. 33:247-251 |
| ISSN: | 1664-2872 0301-1526 |
| DOI: | 10.1024/0301-1526.33.4.247 |
| Popis: | Diagnosis of non-specific aorto-arteritis (NSAA, Takaysu's arteritis) is typically based on clinical and investigational parameters. We report here about two patients with clinically suspected diagnosis of a Takayasu's arteritis already under anti-inflammatory therapy in whom percutaneous transluminal atherectomy of subclavian and axillary artery stenoses was performed to relief the patients from symptoms – intermittent dyspraxia of the arms – and to verify the clinical diagnosis by histology. In the first case aorto-arteritis could be histologically confirmed through the analysis of plaque material including media structures excised from the subclavian and axillary arteries using a new device for atherectomy. The biopsy showed diffuse inflammation and granulomatous lesions with giant cells typically for Takayasu's disease. In the second patient, biopsy showed no acute or chronic inflammatory signs but only atherosclerotic lesions. Percutaneous transluminal atherectomy is therefore not only an interventional but also a diagnostic tool and should be used in every case of interventional therapy of suspected aorto-arteritis to make the clinical diagnosis and as a major consequence the initiation of an aggressive anti-inflammatory medical therapy more reliable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|