The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons

Autor: Bianca Broske, Marianna Tolve, Karen M.J. van Loo, Walid T. Khaled, Ece Öztürk, K. Ushna S. Islam, Sandra Blaess, Stephan L. Baader, Astrid Mentani, Emmanouil Metzakopian, Stefan Britsch, Donato A. Di Monte, Gabriela O. Bodea, Nikolaos Patikas, Pengtao Liu, Ayse Ulusoy, Antonia Wagener
Přispěvatelé: Khaled, Walid [0000-0001-9068-5776], Apollo - University of Cambridge Repository
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
alpha-synuclein
Dopamine
Mice
chemistry.chemical_compound
circuits
metabolism [Dopamine]
metabolism [alpha-Synuclein]
Biology (General)
Induced pluripotent stem cell
skin and connective tissue diseases
transcription factor
metabolism [Repressor Proteins]
Mice
Knockout
Behavior
Animal
metabolism [Dopaminergic Neurons]
Dopaminergic
Neurodegeneration
neurodegeneration
Brain
cytology [Induced Pluripotent Stem Cells]
pathology [Ventral Tegmental Area]
neuronal diversity
metabolism [Induced Pluripotent Stem Cells]
Substantia Nigra
genetics [alpha-Synuclein]
Genetically modified mouse
QH301-705.5
Induced Pluripotent Stem Cells
iPSCs
Substantia nigra
Biology
General Biochemistry
Genetics and Molecular Biology
Midbrain
deficiency [Repressor Proteins]
metabolism [Substantia Nigra]
medicine
Animals
Humans
ddc:610
Transcription factor
development
pathology [Substantia Nigra]
mouse
Alpha-synuclein
dopaminergic neurons
behavior
metabolism [Ventral Tegmental Area]
Ventral Tegmental Area
medicine.disease
Repressor Proteins
genetics [Repressor Proteins]
chemistry
nervous system
metabolism [Brain]
Transcriptome
Neuroscience
Zdroj: Cell reports 36(11), 109697 (2021). doi:10.1016/j.celrep.2021.109697
Cell Reports, Vol 36, Iss 11, Pp 109697-(2021)
Popis: Cell reports 36(11), 109697 (2021). doi:10.1016/j.celrep.2021.109697
Published by Elsevier, [New York, NY]
Databáze: OpenAIRE
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