| Autor: |
Han Wang, Qi Xu, Kaichao Chen, Bill Kwan Wai Chan, Lianwei Ye, Xuemei Yang, Miaomiao Xie, Xiaobo Liu, Hongyuhang Ni, Edward Wai Chi Chan, Sheng Chen |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Microbiology Spectrum. 10 |
| ISSN: |
2165-0497 |
| Popis: |
A plasmid that harbored the virulence factors highly like those of the virulence plasmid commonly found in clinical hypervirulent Klebsiella pneumoniae strains was detected in a foodborne Escherichia coli strain EC1108 and designated p1108-IncFIB. This virulent-like plasmid was found to be common in E. coli from various sources. To understand the contribution of this plasmid to the virulence of E. coli, plasmid p1108-IncFIB in strain EC1108 was first cured to generate strain EC1108-PC. The virulence plasmid p15WZ-82_Vir in Klebsiella pneumoniae strain 15WZ-82 was then transmitted to EC1108-PC to produce the transconjugant, EC1108-PC-TC to assess the contribution of this virulence plasmid to the virulence level of E. coli. During the process of conjugation, p15WZ-82_Vir was found to be evolved into p15WZ-82_int, which underwent homologous recombination with a plasmid encoding a carbapenemase gene |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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