Creutzfeldt-Jakob Disease: In-hospital demographics report of national data in the United States from 2016 and review of a rapidly-progressive case
| Autor: | John H. Cabot, Rebecca Romero, Ali Seifi, Davis H. Payne, José E Cavazos, John V. Lacci, Eithan Kotkowski |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Demographics Adolescent medicine.medical_treatment Ethnic group Disease Creutzfeldt-Jakob Syndrome Article 03 medical and health sciences Young Adult 0302 clinical medicine mental disorders medicine Intubation Humans Age of Onset Healthcare Cost and Utilization Project Child Aged Retrospective Studies Aged 80 and over business.industry Incidence (epidemiology) Brain Infant Retrospective cohort study General Medicine Middle Aged United States nervous system diseases Quartile 030220 oncology & carcinogenesis Child Preschool Disease Progression Surgery Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Clin Neurol Neurosurg |
| ISSN: | 1872-6968 |
| Popis: | Background This report highlights a rapidly progressive case of Creutzfeldt-Jakob Disease (CJD) whose time from symptom onset to death spanned less than two months. We also explore the most recently available in-patient demographics data for discharges with CJD in the United States. Methods We reviewed a CJD case and systematically analyzed a retrospective cohort of CJD discharges using the Healthcare Cost and Utilization Project (HCUP) to evaluate the existing national data on the status of CJD demographics and dispositions in the United States in 2016. Results An estimated total of 710 hospital discharges with a diagnosis of CJD were seen across the United States in 2016. According to HCUP, the average age of patients was 66.15 ± 11.54 years with 48.6 % female. Average time to intubation from admission to hospital was 4.71 ± 7.32 days with a rate of intubation of 6.34 %. The mean hospital cost was $19,901.25 ± $18,743.48. The rate of in-hospital mortality was 8.45 %. No significant geographical differences were noted (p = 0.49). No significant differences were seen among incidence in specific ethnic groups (p = 0.33) or income quartiles (p = 0.90). Conclusions Our data shows that the incidence of CJD in 2016 appears to be equally distributed among individuals in the United States by demographic categories. Additionally, our case-study from 2019 illustrates an important example for diagnosing a rapidly-progressing case of CJD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect