Exercise Training Reverses Gut Dysbiosis in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis: A Proof of Concept Study

Autor: Jessica Dahmus, Regina Lamendella, Gloriany Rivas, Justin P. Wright, Christopher N. Sciamanna, Rohit Loomba, Jeremy R. Chen See, Kathryn H. Schmitz, Jonathan G. Stine, Breianna L. Hummer, Andrew D. Patterson, Alexa Hughes, Mack T. Ruffin
Rok vydání: 2021
Předmět:
Nonalcoholic steatohepatitis
medicine.medical_specialty
Biopsy
Chronic Liver Disease and Cirrhosis
Clinical Sciences
digestive system
Gastroenterology
Proof of Concept Study
Article
Oral and gastrointestinal
Hepatitis
03 medical and health sciences
Liver disease
0302 clinical medicine
Non-alcoholic Fatty Liver Disease
Clinical Research
Internal medicine
Nonalcoholic fatty liver disease
medicine
Animals
Humans
In patient
Exercise
Hepatology
medicine.diagnostic_test
Gastroenterology & Hepatology
business.industry
Prevention
Liver Disease
nutritional and metabolic diseases
medicine.disease
Obesity
digestive system diseases
Gastrointestinal Microbiome
Good Health and Well Being
Liver
030220 oncology & carcinogenesis
Dysbiosis
030211 gastroenterology & hepatology
Gut dysbiosis
business
Digestive Diseases
Zdroj: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 19, iss 8
Clin Gastroenterol Hepatol
Popis: Nonalcoholic fatty liver disease is the leading cause of liver disease worldwide and can progress to nonalcoholic steatohepatitis (NASH) through physical inactivity and gut dysbiosis.1 Exercise training reverses gut dysbiosis in non-NASH persons with obesity and in NASH animal models.2,3 Consequently, we conducted a proof-of-concept study investigating the effect of exercise training on gut dysbiosis in NASH patients.
Databáze: OpenAIRE
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