Efficacy of Gastric Electrical Stimulation for Gastroparesis: US/European Comparison
| Autor: | S. Andersson, Thomas L. Abell, Hasse Abrahamsson, Guillaume Gourcerol, Minesh Mehta, Greger Lindberg, Greg Fullarton, Philippe Ducrotté, Amar Al-Juburi, Chris Lahr, Matt Runnels, Hani Rashed, Jordan Burlen |
|---|---|
| Přispěvatelé: | Université de Louisville, Louisville, KY, USA., Gastrodocs.net, Jackson, MS, USA, University of Goteborg, Sweden., Service d'Hépato-Gastroentérologie [CHU Rouen], Hôpital Charles Nicolle [Rouen]-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Service de physiologie digestive, urinaire, respiratoire et de l'exercice [CHU Rouen], CHU Rouen, Normandie Université (NU)-Hôpital Charles Nicolle [Rouen], Karolinska University Hospital, Stockholm, Sweden, University of Glasgow, Glasgow, Scotland., University of Arkansas for Medical Sciences, Little Rock, AR, USA., Medical University of South Carolina, Charleston, SC, USA, The University of Tennessee Health Science Center [Memphis] (UTHSC) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Gastric electrical stimulation
medicine.medical_specialty Gastroparesis Statistical difference 03 medical and health sciences 0302 clinical medicine Nausea and vomiting Internal medicine Statistical significance Diabetes mellitus medicine Gastric emptying business.industry Diabetes Significant difference [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology medicine.disease 3. Good health Exact test 030220 oncology & carcinogenesis Health delivery Original Article 030211 gastroenterology & hepatology business |
| Zdroj: | Gastroenterology Research Gastroenterology Research, Elmer Press, 2018, 11 (5), pp.349-354. ⟨10.14740/gr1061w⟩ |
| ISSN: | 1918-2805 1918-2813 |
| DOI: | 10.14740/gr1061w⟩ |
| Popis: | International audience; Background: Gastric electrical stimulation (GES) is used in both the US and Europe, but little research has investigated the demographics of gastroparesis patients receiving GES by geographic location.Methods: We compared data from 380 patients, 296 female and 84 males, mean age 42 years, 246 idiopathic (ID), 107 diabetic (DM), and 27 post-surgical (PS). The statistical significance was calculated by Chi-square test and a P-value obtained for ID, DM, and PS. The statistical significance was calculated by Fischer exact test and a P-value obtained comparing male vs. female.Results: European centers had 61 GES patients compared to 319 from the US. In Europe, 100% of patients had gastric emptying test (GET) values available; in the US, it was 75% of patients. European centers had more DM patients (59%) than the US (22%), and a smaller proportion of ID patients (25%) than the US (72%). There was a statistical difference between the causes of gastroparesis in the patients receiving GES (P-value < 0.00001). There was also significant difference in the gender of the patients receiving GES, with a greater proportion of women in the US (P value = 0.0023).Conclusions: Comparing GES in US vs. Europe demonstrated significant differences in gastroparesis demographics and percentage of patients with GET data. After analyzing the previously discussed results and reviewing recent updates in evidence-based medicine guidelines, the discrepancy and variance in patient populations in the US and Europe emphasizes the need for a database that allows better analysis and treatment of gastroparesis patients worldwide including stimulation therapies. |
| Databáze: | OpenAIRE |
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