| Autor: |
A. Cereda, L. Allievi, A. Palmisano, G. Tumminello, L. Barbieri, A. Mangieri, A. Laricchia, A. Khokhar, F. Giannini, M. Toselli, G. M. Sangiorgi, A. Esposito, P. Aseni, S. Lucreziotti, A. Mafrici, S. Carugo |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Emergency radiology. 29(4) |
| ISSN: |
1438-1435 |
| Popis: |
Chest CT is valuable to detect alternative diagnoses/complications of COVID-19, while its role for prognostication requires further investigation. Non-pulmonary radiological findings such as cardiovascular calcifications could increase the predictivity of clinical outcomes of COVID-19 patients beyond pulmonary involvement. Several observational studies have reported mixed results on the role of coronary calcifications in COVID-19 patients as a predictor of hospitalization, ventilatory support, and mortality. The purpose of the study is to systematically review the available evidence on the predictive role of cardiovascular calcifications in SARS-CoV2 disease. The meta-analysis confirms the prognostic significance of coronary calcifications on hospital mortality, and coronary calcifications (CAC ≠ 0) were associated with an OR for mortality of 2.19 (95% CI 1.36-3.52). CAC was neutral on respiratory outcomes, but it was associated with an increased trend of cardiovascular events. Coronary calcium appears as a promising biomarker imaging even in short-term outcomes (MACEs, hospital mortality) in a non-cardiovascular disease such as Sars-CoV2 infection. Further large studies are needed to confirm promising results of this imaging biomarker in non-cardiovascular disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink