New Nanotechnologies for the Treatment and Repair of Skin Burns Infections
Autor: | Maria C. Teixeira, Andréa Arruda Martins Shimojo, Eliana B. Souto, Selma B. Souto, André F Ribeiro, José L Soriano, Maria Inês Ferreira, Massimo Lucarini, Antonello Santini, Alessandra Durazzo, Beatriz Clares Naveros |
---|---|
Přispěvatelé: | Souto, Eliana B, Ribeiro, André F, Ferreira, Maria I, Teixeira, Maria C, Shimojo, Andrea A M, Soriano, José L, Naveros, Beatriz C, Durazzo, Alessandra, Lucarini, Massimo, Souto, Selma B, Santini, Antonello, Universidade do Minho |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Antibiotics wound healing 02 engineering and technology Review antibiotics lcsh:Chemistry Systemic antibiotics antibiotic lcsh:QH301-705.5 Spectroscopy Skin Burn wound integumentary system nanoparticle General Medicine Skin integrity 021001 nanoscience & nanotechnology 3. Good health Computer Science Applications Anti-Bacterial Agents 0210 nano-technology Burns medicine.medical_specialty medicine.drug_class Catalysis Inorganic Chemistry Sepsis 03 medical and health sciences Antibiotic resistance medicine Humans Physical and Theoretical Chemistry Intensive care medicine Molecular Biology Wound Healing Science & Technology Tissue Engineering business.industry Organic Chemistry medicine.disease burn wound infection Bandages 030104 developmental biology lcsh:Biology (General) lcsh:QD1-999 Wound dressing Wound Infection Nanoparticles nanoparticles business Wound healing |
Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 21, Iss 2, p 393 (2020) Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
ISSN: | 1422-0067 |
Popis: | Burn wounds are highly debilitating injuries, with significant morbidity and mortality rates worldwide. In association with the damage of the skin integrity, the risk of infection is increased, posing an obstacle to healing and potentially leading to sepsis. Another limitation against healing is associated with antibiotic resistance mainly due to the use of systemic antibiotics for the treatment of localized infections. Nanotechnology has been successful in finding strategies to incorporate antibiotics in nanoparticles for the treatment of local wounds, thereby avoiding the systemic exposure to the drug. This review focuses on the most recent advances on the use of nanoparticles in wound dressing formulations and in tissue engineering for the treatment of burn wound infections. The authors would like to thank the financial support received from Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) under the project references M-ERA-NET/0004/2015-PAIRED and UIDB/04469/2020, co-financed by FEDER, under the Partnership Agreement PT2020. info:eu-repo/semantics/publishedVersion |
Databáze: | OpenAIRE |
Externí odkaz: |