New Nanotechnologies for the Treatment and Repair of Skin Burns Infections

Autor: Maria C. Teixeira, Andréa Arruda Martins Shimojo, Eliana B. Souto, Selma B. Souto, André F Ribeiro, José L Soriano, Maria Inês Ferreira, Massimo Lucarini, Antonello Santini, Alessandra Durazzo, Beatriz Clares Naveros
Přispěvatelé: Souto, Eliana B, Ribeiro, André F, Ferreira, Maria I, Teixeira, Maria C, Shimojo, Andrea A M, Soriano, José L, Naveros, Beatriz C, Durazzo, Alessandra, Lucarini, Massimo, Souto, Selma B, Santini, Antonello, Universidade do Minho
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Antibiotics
wound healing
02 engineering and technology
Review
antibiotics
lcsh:Chemistry
Systemic antibiotics
antibiotic
lcsh:QH301-705.5
Spectroscopy
Skin
Burn wound
integumentary system
nanoparticle
General Medicine
Skin integrity
021001 nanoscience & nanotechnology
3. Good health
Computer Science Applications
Anti-Bacterial Agents
0210 nano-technology
Burns
medicine.medical_specialty
medicine.drug_class
Catalysis
Inorganic Chemistry
Sepsis
03 medical and health sciences
Antibiotic resistance
medicine
Humans
Physical and Theoretical Chemistry
Intensive care medicine
Molecular Biology
Wound Healing
Science & Technology
Tissue Engineering
business.industry
Organic Chemistry
medicine.disease
burn wound infection
Bandages
030104 developmental biology
lcsh:Biology (General)
lcsh:QD1-999
Wound dressing
Wound Infection
Nanoparticles
nanoparticles
business
Wound healing
Zdroj: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 2, p 393 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ISSN: 1422-0067
Popis: Burn wounds are highly debilitating injuries, with significant morbidity and mortality rates worldwide. In association with the damage of the skin integrity, the risk of infection is increased, posing an obstacle to healing and potentially leading to sepsis. Another limitation against healing is associated with antibiotic resistance mainly due to the use of systemic antibiotics for the treatment of localized infections. Nanotechnology has been successful in finding strategies to incorporate antibiotics in nanoparticles for the treatment of local wounds, thereby avoiding the systemic exposure to the drug. This review focuses on the most recent advances on the use of nanoparticles in wound dressing formulations and in tissue engineering for the treatment of burn wound infections.
The authors would like to thank the financial support received from Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) under the project references M-ERA-NET/0004/2015-PAIRED and UIDB/04469/2020, co-financed by FEDER, under the Partnership Agreement PT2020.
info:eu-repo/semantics/publishedVersion
Databáze: OpenAIRE
Externí odkaz: