Hypertensive disorders in normal/over-weight and obese type 2 diabetic pregnant women

Autor: A. Napoli, P. Bianchi, A. Colatrella, C Festa, S. Braucci, F Fallucca, Trappolini M, Luca Mattei
Rok vydání: 2009
Předmět:
Zdroj: Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 117(8)
ISSN: 1439-3646
Popis: Background: Hypertension is one of the major complications of pregnancy. Its impact in type 2 diabetic pregnant women could be understimated because it is generally evaluated by retrospective studies and as one of the outcome measures. Objective: Our aims were: 1) to evaluate the prevalence of hypertensive disease between type 2 diabetic and normal pregnancies; 2) to relate hypertensive disease to body weight in type 2 diabetic pregnancies; 3) to assess the impact of different types of hypertension on pregnancy outcome in type 2 diabetic women. Study Design: Seventy-six type 2 diabetic (23 normal-weight, 26 overweight and 27 obese) and sixty normal (43, 15 and 2 respectively; x 2 0.0001) pregnancies, matched for age and smoking habit. Hypertension was defined as ≥ 140/ 90 mmHg and classified in chronic, gestational and pre-eclampsia. Statistical Analysis: Student's t-test, X 2 , simple, and/or multiple and logistic regression analysis were used when appropriate. Odds ratio was calculated for hypertension. p significant < 0.05. Results: The overall prevalence of hypertension was 40.8 % (18.4% chronic, 17.1 % gestational and 5.3 % pre-eclampsia) in type 2 diabetic pregnancies and 10 % (8.3 % gestational and 1.7% pre-eclampsia) in normal pregnancies (p
Databáze: OpenAIRE