'Click to Chelate' : Synthesis and installation of metal chelates into biomolecules in a single step
| Autor: | Luc Brans, Roger Schibli, Veronique Maes, Todor Anguelov, D. Tourwe, Harriet Struthers, Thomas L. Mindt, Christian Schweinsberg |
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| Přispěvatelé: | Chemistry |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Azides
Denticity Triazole Biochemistry Chemical synthesis Catalysis Metal chemistry.chemical_compound Colloid and Surface Chemistry otorhinolaryngologic diseases Organic chemistry Molecule Chelation Chelating Agents chemistry.chemical_classification Alanine Biomolecule General Chemistry Triazoles Combinatorial chemistry chemistry Metals visual_art Alkynes Isotope Labeling visual_art.visual_art_medium Click chemistry peptides |
| Popis: | Click chemistry has been employed for the assembly of novel and efficient triazole-based multidentate chelating systems while simultaneously attaching them to molecules of biological interest. The "click-to-chelate" approach offers a powerful new tool for the modification of (bio)molecules with metal chelators for potential diagnostic and therapeutic applications. |
| Databáze: | OpenAIRE |
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