Effect of cardiorespiratory fitness on short-term morbidity and mortality after coronary artery bypass grafting
| Autor: | Thomas A. Verrill, Marc P. Sakwa, Francis Shannon, Barry A. Franklin, Judy A. Boura, James L. Smith |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Michigan Time Factors Bypass grafting Heart disease Health Status Preoperative risk Myocardial Ischemia Risk Assessment Postoperative Complications Risk Factors Internal medicine Cause of Death Medicine Humans Coronary Artery Bypass Cardiovascular mortality Aged Retrospective Studies business.industry Medical record Retrospective cohort study Cardiorespiratory fitness Middle Aged medicine.disease Prognosis surgical procedures operative medicine.anatomical_structure Physical Fitness Preoperative Period Cardiology Exercise Test Female Morbidity Cardiology and Cardiovascular Medicine business Artery Follow-Up Studies |
| Zdroj: | The American journal of cardiology. 112(8) |
| ISSN: | 1879-1913 |
| Popis: | Although preoperative risk assessment for coronary artery bypass grafting (CABG) has been evaluated with multiple predictive models, none have incorporated a low level of cardiorespiratory fitness, which represents one of the strongest predictors of all-cause and cardiovascular mortality in subjects with and without heart disease. The aim of the present study was to evaluate preoperative cardiorespiratory fitness, expressed as METs (1 MET = 3.5 ml O2/kg/min), and short-term morbidity and mortality after CABG. The Society of Thoracic Surgeons database was queried for patients who underwent CABG from January 2002 to December 2010 at Beaumont Health Systems. Electronic medical records were reviewed for peak or symptom-limited exercise testing90 days before CABG. Peak METs were estimated from the achieved treadmill speed, grade, and duration or the cycle ergometer workload, corrected for body weight. Patients who met eligibility criteria (n = 596) were categorized into 2 groups: those with reduced aerobic capacity (5 METs [n = 78]) and those achieving ≥5 METs (n = 518). Fisher's exact tests were used to compare preoperative aerobic capacity and short-term postoperative morbidity and mortality between the 2 groups. After adjusting for potential confounding variables, an inverse relation was found between cardiorespiratory fitness and complications after CABG. Specifically, low preoperative cardiorespiratory fitness (5 METs) was associated with higher operative and 30-day mortality after CABG (p0.05). In conclusion, these data suggest that preoperative cardiorespiratory fitness provides an independent and additive marker for mortality after CABG. |
| Databáze: | OpenAIRE |
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