Non-sexually related acute genital ulcers in 13 pubertal girls: a clinical and microbiological study
| Autor: | Marie-Françoise Avril, Monique Pelisse, David Farhi, Jacqueline Raynal, Emmanuel Molinari, Jeanne Wendling, Guislaine Carcelain, Nicolas Dupin, Patrice Morand, Flore Rozenberg, Camille Francès |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Epstein-Barr Virus Infections Adolescent Igm antibody Dermatology Virus Serology Diagnosis Differential Internal medicine Lipschütz ulcer Medicine Humans Sex organ Child Ulcer business.industry Behcet disease Behcet Syndrome General Medicine University hospital medicine.disease Surgery Acute Disease Etiology Female Vulvar Diseases business |
| Zdroj: | Archives of dermatology. 145(1) |
| ISSN: | 1538-3652 |
| Popis: | Objective To describe the clinical and microbiological features of acute genital ulcers (AGU), which have been reported in virgin adolescents, predominantly in girls. Design Descriptive study. We collected data on the clinical features, sexual history, blood cell count, biochemistry, microbiological workup, and 1-year follow-up. Setting Departments of dermatology of 3 university hospitals in Paris. Patients Thirteen immunocompetent female patients with a first flare of non–sexually transmitted AGU. Main Outcome Measures Clinical and microbiological data, using a standardized form. Results Mean age was 16.6 years (range, 11-19 years). Eleven patients denied previous sexual contact. A fever or flulike symptoms preceded AGU in 10 of the 13 patients (77%), with a mean delay of 3.8 days before the AGU onset (range, 0-10 days). The genital ulcers were bilateral in 10 patients. The final diagnosis was Epstein-Barr virus primary infection in 4 patients (31%) and Behcet disease in 1 patient (8%). No other infectious agents were detected in this series. Conclusions We recommend serologic testing for Epstein-Barr virus with IgM antibodies to viral capsid antigens in non–sexually related AGU in immunocompetent patients. Further microbiological studies are required to identify other causative agents. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|