High-Frequency Oscillations Recorded on the Scalp of Patients With Epilepsy Using Tripolar Concentric Ring Electrodes
| Autor: | Andrei V. Medvedev, Robert S. Fisher, Walter G. Besio, Andrew S. Blum, Oleksandr Makeyev, John N. Gaitanis, Iris E. Martínez-Juárez |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
lcsh:Medical technology 0206 medical engineering Biomedical Engineering 02 engineering and technology Neurological disorder Electroencephalography lcsh:Computer applications to medicine. Medical informatics Alpha wave Article Concentric ring 03 medical and health sciences Epilepsy 0302 clinical medicine Nuclear magnetic resonance Signal quality tripolar concentric ring electrode sensors medicine high-frequency oscillations medicine.diagnostic_test business.industry General Medicine medicine.disease 020601 biomedical engineering Surgery Neurovascular Devices and Systems medicine.anatomical_structure lcsh:R855-855.5 Scalp Electrode epilepsy lcsh:R858-859.7 Laplacian business 030217 neurology & neurosurgery |
| Zdroj: | IEEE Journal of Translational Engineering in Health and Medicine, Vol 2, Pp 1-11 (2014) IEEE Journal of Translational Engineering in Health and Medicine |
| ISSN: | 2168-2372 |
| DOI: | 10.1109/jtehm.2014.2332994 |
| Popis: | Epilepsy is the second most prevalent neurological disorder (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{upgreek} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} }{}\(\sim 1\) \end{document}% prevalence) affecting \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{upgreek} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} }{}\(\sim 67\) \end{document} million people worldwide with up to 75% from developing countries. The conventional electroencephalogram is plagued with artifacts from movements, muscles, and other sources. Tripolar concentric ring electrodes automatically attenuate muscle artifacts and provide improved signal quality. We performed basic experiments in healthy humans to show that tripolar concentric ring electrodes can indeed record the physiological alpha waves while eyes are closed. We then conducted concurrent recordings with conventional disc electrodes and tripolar concentric ring electrodes from patients with epilepsy. We found that we could detect high frequency oscillations, a marker for early seizure development and epileptogenic zone, on the scalp surface that appeared to become more narrow-band just prior to seizures. High frequency oscillations preceding seizures were present in an average of 35.5% of tripolar concentric ring electrode data channels for all the patients with epilepsy whose seizures were recorded and absent in the corresponding conventional disc electrode data. An average of 78.2% of channels that contained high frequency oscillations were within the seizure onset or irritative zones determined independently by three epileptologists based on conventional disc electrode data and videos. Electroencephalography (EEG) is a noninvasive means for recording electrical activity of the brain. We have developed tripolar concentric ring electrodes (TCREs) and have shown that TCREs provide higher signal-to-noise ratios, higher spatial resolution, and less mutual information than conventional disc electrodes. This paper describes the results of a clinical study of patients with epilepsy to determine if high-frequency oscillations (HFOs) were present in EEG recorded with TCREs. |
| Databáze: | OpenAIRE |
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