Refining the rat sciatic nerve block: a novel ultrasound-guided technique
| Autor: | Gregory Booth, Scott Hughey, Jason Longwell, Jacob Cole, Donald Campbell, Kamala Rapp-Santos, Eric Stedje-Larsen |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Pathology medicine.medical_specialty Injections Rats Sprague-Dawley 03 medical and health sciences Mice 0302 clinical medicine Sciatic nerve block 030202 anesthesiology Cadaver Medicine Animals Humans Ultrasonography Interventional General Veterinary business.industry Nerve Block Sciatic Nerve Ultrasound guided Staining Rats Ultrasound guidance Murine model Animal Science and Zoology Sciatic nerve business Cadaveric spasm 030217 neurology & neurosurgery |
| Zdroj: | Laboratory animals. 56(2) |
| ISSN: | 1758-1117 |
| Popis: | Murine translational models are an important tool to understand pain pathophysiology. One procedure used frequently in murine research is the sciatic nerve block. This study sought to demonstrate the use of ultrasound-guided sciatic nerve block in a cadaveric murine model. A total of 40 injections were performed in 20 Sprague–Dawley male 18-month-old rat cadavers. Necropsy was performed to identify staining of the sciatic nerve. Staining with methylene blue occurred in 40 of 40 ultrasound-guided injections. The extremely accurate nature of this block under ultrasound guidance is favorable for future translational studies in rats undergoing sciatic nerve blocks. This method may represent a significant improvement in current methods. |
| Databáze: | OpenAIRE |
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