Decision-making ability in current and past users of opiates: A meta-analysis
| Autor: | Skye N. McLennan, Peter G. Rendell, Gill Terrett, Izelle Labuschagne, Kathryn Biernacki |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
cognition
medicine.medical_specialty Substance-Related Disorders Cognitive Neuroscience media_common.quotation_subject Decision Making impulsivity Poison control Neuropsychological Tests Impulsivity 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine abstinent Injury prevention medicine Humans Psychiatry Opiate alkaloid media_common Opiate Alkaloids Addiction decision-making Abstinence Iowa gambling task opiate 030227 psychiatry Neuropsychology and Physiological Psychology Gambling addiction medicine.symptom Opiate heroin Psychology 030217 neurology & neurosurgery |
| Zdroj: | Neuroscience & Biobehavioral Reviews. 71:342-351 |
| ISSN: | 0149-7634 |
| DOI: | 10.1016/j.neubiorev.2016.09.011 |
| Popis: | Opiate use is associated with deficits in decision-making. However, the impact of abstinence and co-morbid factors, like head injury and poly-substance abuse, on this ability, is currently unclear. This meta-analysis aimed to assess 1) the magnitude of decision-making deficits in opiate users; 2) whether co-morbid factors moderate the severity of these deficits; 3) whether ex-opiate users demonstrate smaller decision-making deficits than current users; and 4) whether the length of abstinence is related to the magnitude of decision-making deficits. We analysed 22 studies that compared the performance of current and ex-opiate users to healthy controls on decision-making measures such as the Iowa Gambling Task. Current users demonstrated a moderately strong impairment in decision-making relative to controls, which was not significantly moderated by co-morbid factors. The magnitude of the impairment did not significantly differ between studies assessing current or ex-users, and this impairment was not related to length of abstinence. Thus, it appears that opiate users have relatively severe decision-making deficits that persist at least 1.5 years after cessation of use. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect