A clinical trial to evaluate the effect of the Mediterranean diet on smokers lung function
| Autor: | Mar Sorlí-Aguilar, Teresa Canela-Armengol, Rosa Maria Valls-Zamora, Victoria Arija-Val, Rosa Solà-Alberich, Antoni Santigosa-Ayala, Patricia Salamanca-González, Roxana-Elena Catalin, Francisco Martin-Lujan, Nuria Martin-Vergara |
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| Přispěvatelé: | [Martín-Luján F] Institut Català de la Salut, CAP El Morell, Institut Universitari d'Investigació en Atenció Primària-IDIAP Jordi Gol, School of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain. [Catalin RE] Institut Català de la Salut, CAP Bonavista, Tarragona, Spain. [Salamanca-González P, Sorlí-Aguilar M] Research Support Unit Tarragona-Reus, Institut Universitari d'Investigació en Atenció Primària-IDIAP Jordi Gol, Tarragona, Spain. [Santigosa-Ayala A] Institut Català de la Salut, CAP Sant Salvador, Institut Universitari d'Investigació en Atenció Primària-IDIAP Jordi Gol, School of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain. [Valls-Zamora RM, Solà-Alberich R] Hospital Universitari Sant Joan, Institut d'Investigació Sanitària Pere Virgili (IISPV), Functional Nutrition, Oxidation and Cardiovascular Disease (NFOC-SALUT) group, Universitat Rovira i Virgili, Reus, Spain. [Martín-Vergara N] Institut Català de la Salut, CAP Horts de Miró, Tarragona, Spain. [Canela-Armengol T] Institut Català de la Salut, CAP Dr Sarro, Tarragona, Spain. [Arija-Val V] Institut Universitari d'Investigació en Atenció Primària-IDIAP Jordi Gol, School of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain, IDIAP Jordi Gol |
| Rok vydání: | 2018 |
| Předmět: |
Male
Mediterranean diet medicine.medical_treatment Pilot Projects Diet Mediterranean Dieta mediterrània Pulmonary function testing law.invention Pulmonary Disease Chronic Obstructive 0302 clinical medicine Randomized controlled trial Informed consent law Nutritional supplements Protocol 030212 general & internal medicine Fumadors Lung education.field_of_study medicine.diagnostic_test Smoking personas::fumadores [DENOMINACIONES DE GRUPOS] Middle Aged Clinical trial design Female Pulmonary and Respiratory Medicine Spirometry Adult medicine.medical_specialty Population terapéutica::terapia nutricional::dietoterapia::dieta mediterránea [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS] 03 medical and health sciences Internal medicine sistema respiratorio::pulmón [ANATOMÍA] medicine Humans education Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT] Aged lcsh:RC705-779 Primary Health Care business.industry Public Health Environmental and Occupational Health lcsh:Diseases of the respiratory system Respiratory System::Lung [ANATOMY] Clinical trial 030228 respiratory system Pulmons Smoking cessation Smoking Cessation Persons::Smokers [NAMED GROUPS] business |
| Zdroj: | NPJ Primary Care Respiratory Medicine Scientia npj Primary Care Respiratory Medicine, Vol 29, Iss 1, Pp 1-6 (2019) |
| ISSN: | 2055-1010 |
| Popis: | Mediterranian diet; Smoke; Lung function Dieta mediterránea; Fumar; Función pulmonar Dieta mediterrània; Fumar; Funció pulmonar Data on the association between lung function and some dietary patterns have been published. However, it is not yet well known if whether the Mediterranean Diet (MD) pattern can preserve or improve lung function. Our purpose is to evaluate the effect of increased MD adherence on lung function in smokers. A multicenter, parallel, cluster-randomized, controlled clinical trial is proposed. A total of 566 active smokers (>10 packs-year), aged 25-75 years will be included, without previous respiratory disease and who sign an informed consent to participate. Twenty Primary Care Centres in Tarragona (Spain) will be randomly assigned to a control or an intervention group (1:1). All participants will receive advice to quit smoking, and the intervention group, a nutritional intervention (2 years) designed to increase MD adherence by: (1) annual visit to deliver personalized nutritional education, (2) annual telephone contact to reinforce the intervention, and (3) access to an online dietary blog. We will evaluate (annually for 2 years): pulmonary function by forced spirometry and MD adherence by a 14-item questionnaire and medical tests (oxidation, inflammation and consumption biomarkers). In a statistical analysis by intention-to-treat basis, with the individual smoker as unit of analysis, pulmonary function and MD adherence in both groups will be compared; logistic regression models will be applied to analyze their associations. We hope to observe an increased MD adherence that may prevent the deterioration of lung function in smokers without previous respiratory disease. This population may benefit from a dietary intervention, together with the recommendation of smoking cessation. |
| Databáze: | OpenAIRE |
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