Social Cognition in Individuals at Ultra-High Risk for Psychosis: A Meta-Analysis
| Autor: | Gerdina H. M. Pijnenborg, Roeline Nieboer, R. J. M. van Donkersgoed, Lex Wunderink, André Aleman |
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| Přispěvatelé: | Clinical Psychology and Experimental Psychopathology, Clinical Neuropsychology, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Perceptual and Cognitive Neuroscience (PCN), Clinical Cognitive Neuropsychiatry Research Program (CCNP) |
| Rok vydání: | 2015 |
| Předmět: |
Psychosis
medicine.medical_specialty HEALTHY CONTROLS Theory of Mind lcsh:Medicine FACIAL AFFECT RECOGNITION Neuropsychological Tests Ultra high risk Biology CONTROLLED-TRIAL law.invention 1ST-EPISODE SCHIZOPHRENIA Cognition Randomized controlled trial Social cognition law 1ST-DEGREE RELATIVES Theory of mind medicine Humans CLINICAL HIGH-RISK lcsh:Science Social Behavior Psychiatry 1ST EPISODE PSYCHOSIS EMOTION RECOGNITION Multidisciplinary lcsh:R medicine.disease Psychotic Disorders Meta-analysis PRODROMAL PSYCHOSIS lcsh:Q UNTREATED PSYCHOSIS Social cognitive theory Research Article |
| Zdroj: | PLoS ONE, 10(10):e0141075. PUBLIC LIBRARY SCIENCE PLoS ONE PLoS ONE, Vol 10, Iss 10, p e0141075 (2015) |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0141075 |
| Popis: | ObjectiveTreatment in the ultra-high risk stage for a psychotic episode is critical to the course of symptoms. Markers for the development of psychosis have been studied, to optimize the detection of people at risk of psychosis. One possible marker for the transition to psychosis is social cognition. To estimate effect sizes for social cognition based on a quantitative integration of the published evidence, we conducted a meta-analysis of social cognitive performance in people at ultra high risk (UHR).MethodsA literature search (1970-July 2015) was performed in PubMed, PsychINFO, Medline, Embase, and ISI Web of Science, using the search terms 'social cognition', 'theory of mind', 'emotion recognition', 'attributional style', 'social knowledge', 'social perception', 'empathy', 'at risk mental state', 'clinical high risk', 'psychosis prodrome', and 'ultra high risk'. The pooled effect size (Cohen's D) and the effect sizes for each domain of social cognition were calculated. A random effects model with 95% confidence intervals was used.ResultsSeventeen studies were included in the analysis. The overall significant effect was of medium magnitude (d = 0.52, 95% CI = 0.38-0.65). No moderator effects were found for age, gender and sample size. Sub-analyses demonstrated that individuals in the UHR phase show significant moderate deficits in affect recognition and affect discrimination in faces as well as in voices and in verbal Theory of Mind (TOM). Due to an insufficient amount of studies, we did not calculate an effect size for attributional bias and social perception/knowledge. A majority of studies did not find a correlation between social cognition deficits and transition to psychosis, which may suggest that social cognition in general is not a useful marker for the development of psychosis. However some studies suggest the possible predictive value of verbal TOM and the recognition of specific emotions in faces for the transition into psychosis. More research is needed on these subjects.ConclusionThe published literature indicates consistent general impairments in social cognition in people in the UHR phase, but only very specific impairments seem to predict transition to psychosis. |
| Databáze: | OpenAIRE |
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