Cardiovascular considerations in management of patients with Turner syndrome

Autor: Maria Stefil, Agnieszka Kotalczyk, Joanne C. Blair, Gregory Y.H. Lip
Rok vydání: 2023
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Zdroj: Stefil, M, Kotalczyk, A, Blair, J & Lip, G Y H 2023, ' Cardiovascular considerations in management of patients with Turner syndrome ', Trends in Cardiovascular Medicine, vol. 33, no. 3, pp. 150-158 . https://doi.org/10.1016/j.tcm.2021.12.002
ISSN: 1050-1738
DOI: 10.1016/j.tcm.2021.12.002
Popis: Turner syndrome (TS) is a chromosomal disorder that affects 25-50 per 100,000 live born females. Patients with TS face a heavy burden of cardiovascular disease (congenital and acquired) with an increased risk of mortality and morbidity compared to the general population. Cardiovascular diseases are a major cause of death in females with TS. Approximately 50% of TS patients have a congenital heart abnormality, with a high incidence of bicuspid aortic valve (BAV), coarctation of the aorta (CoA) and generalised arteriopathy. Frequently, females with TS have systemic hypertension, which is also a risk factor for progressive cardiac dysfunction and aortopathy. This paper aims to provide an overview of the cardiovascular assessment, management and follow up strategies in this high-risk population of TS patients.
Databáze: OpenAIRE
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