Estrogen and Progesterone Receptor Content in Bilateral Breast Cancer
| Autor: | I. Spužić, Mirjana Branković-Magić, Nikolić-Vukosavljević D, Z. Nešković Konstantinović, Ksenija Kanjer |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
medicine.medical_specialty medicine.drug_class medicine.medical_treatment Breast Neoplasms Pathology and Forensic Medicine Steroid Neoplasms Multiple Primary Internal medicine Progesterone receptor Histologic type Humans Medicine Receptor Estrogen receptor beta Aged business.industry Carcinoma Cell Biology Middle Aged Bilateral breast cancer Endocrinology Receptors Estrogen Estrogen Lymphatic Metastasis Receptors Progesterone business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0344-0338 |
| DOI: | 10.1016/s0344-0338(11)80917-9 |
| Popis: | Summary Estrogen and progesterone receptor content was determined in 34 patients with synchronous and 23 patients with asynchronous bilateral breast cancer. Steroid receptor content was measured quantitatively by DCC method. It was shown that progesterone receptor content could not be predicted, as well as, that steroid receptor content of the second tumor significantly influenced the development of asynchronous bilateral breast cancer. The high discordance rate concerning histologic type between two tumors within synchronous as well as asynchronous biopsies was observed. The obtained results indicate that both synchronous and asynchronous bilateral breast tumors may be considered as biologically different tumors whose both steroid receptor levels should be determined whenever possible. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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