Bone material ultrasound velocity is predictive of whole bone strength
| Autor: | Dwight G Bronson, Peter P. Antich, Shreefal Mehta, M Daphtary, Edmond Richer |
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| Rok vydání: | 2001 |
| Předmět: |
Materials science
Acoustics and Ultrasonics Ovariectomy Biophysics In Vitro Techniques Bone tissue Bone and Bones Bone strength medicine Animals Radiology Nuclear Medicine and imaging Femur Reflectometry Ultrasonography Bone Development Radiological and Ultrasound Technology business.industry Ultrasound Biomechanics Stiffness Anatomy Biomechanical Phenomena Rats medicine.anatomical_structure Female Ultrasonic sensor medicine.symptom business Biomedical engineering |
| Zdroj: | Ultrasound in Medicine & Biology. 27:861-867 |
| ISSN: | 0301-5629 |
| DOI: | 10.1016/s0301-5629(01)00385-4 |
| Popis: | In humans, bone strength is assessed indirectly by the noninvasive measurement of structure or mass. Recent clinical application of an ultrasonic critical-angle reflectometry technique (UCR) has demonstrated the measurement of the regional and directional distribution of mechanical stiffness. This study investigates the specific question: are these measurements of a local material level property predictive of the strength of whole bone? Maximum values of pressure wave velocity and breaking strength were recorded at two locations (midshaft and base of neck) on rat femurs from growing rats. The results demonstrate a strong empirical relationship between material-level ultrasound (US) velocity and whole bone mechanical strength. However, the US velocity at a specific bone site can be used to assess bone strength at that site only, explaining discrepancies in other published studies that negate a relationship between strength and US velocity. The results indicate an important role for US velocity measurement in clinical evaluation of bone health. |
| Databáze: | OpenAIRE |
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