Arsenicosis in bladder pathology and schistosomiasis in Eggua, Nigeria
| Autor: | Raphael D. Isokpehi, Shukurat O Bakare, Adewale S Adebayo, Olugbenga S Onile, Chiaka I. Anumudu, Atinuke M Agunloye, H.O. Awobode |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 0301 basic medicine Pathology medicine.medical_specialty Adolescent Urinalysis Urinary system Urinary Bladder 030106 microbiology 030231 tropical medicine Nigeria chemistry.chemical_element Schistosomiasis Urine Arsenic Schistosomiasis haematobia Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Water Supply Prevalence medicine Animals Humans Parasite Egg Count Microscopy Bladder cancer medicine.diagnostic_test business.industry Genitourinary system Public Health Environmental and Occupational Health Environmental Exposure General Medicine Middle Aged medicine.disease Epidemiologic Studies Infectious Diseases Urinary Bladder Neoplasms chemistry Schistosoma haematobium Population study Female Parasitology business Water Pollutants Chemical |
| Zdroj: | Transactions of The Royal Society of Tropical Medicine and Hygiene. 112:230-237 |
| ISSN: | 1878-3503 0035-9203 |
| DOI: | 10.1093/trstmh/try047 |
| Popis: | Background Chronic schistosomiasis and arsenic exposure through drinking water are some of the risk factors for bladder cancer. To determine the association of schistosomiasis and arsenicosis with bladder pathologies, 122 individuals from Eggua in southwest Nigeria were recruited for this study. Methods Prevalence of schistosomiasis was determined by urine microscopy and PCR. Total urinary arsenic concentration and arsenic levels in three different water sources in the community were assessed by flame atomic absorption spectrometry. Bladder pathologies were investigated by ultrasonography. The data collected were evaluated with chi-square (χ2) and ANOVA tests to examine the relationships among demographic factors, infection, bladder pathologies and urinary arsenic concentrations. Results The prevalence and mean intensity of schistosomiasis were 21.3% and 20.7 eggs/10 mL urine, respectively. Arsenic concentration in two of the water sources, River Yewa (0.46 mg/L) and borehole (0.52 mg/L), were above the WHO standard (0.01 mg/L); and the mean concentration in urine samples, 1.17 mg/L, was also above the WHO standard (0.2 mg/L). There was no evidence of an association between bladder pathology and arsenicosis, or between schistosomiasis associated-bladder pathology and arsenicosis (p=0.66). Conclusions Arsenicosis is a public health concern in the study population. At the moment no clear roles are envisaged for it in the development of bladder pathologies or urinary schistosomiasis-associated bladder pathologies in Eggua. |
| Databáze: | OpenAIRE |
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