Light–moderate alcohol consumption and left ventricular function among healthy, middle-aged adults: the HUNT study
Autor: | Staffan Ahnve, Lars J. Vatten, Imre Janszky, Katalin Gémes, Linn B Strand, Kenneth J. Mukamal, Krisztina László, Håvard Dalen |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Adult
Male medicine.medical_specialty moderate alcohol consumption Alcohol Drinking Epidemiology Heart Ventricles Population Binge drinking Physical examination Speckle tracking echocardiography 030204 cardiovascular system & hematology Ventricular Function Left 03 medical and health sciences 0302 clinical medicine Hunt study Internal medicine Surveys and Questionnaires medicine echocardiography Humans 030212 general & internal medicine education cardiac epidemiology Aged education.field_of_study medicine.diagnostic_test business.industry Norway Research General Medicine Middle Aged Echocardiography Doppler Healthy Volunteers Cross-Sectional Studies Multivariate Analysis Cardiology Linear Models Female business Alcohol consumption |
Zdroj: | BMJ Open |
ISSN: | 2044-6055 |
Popis: | Objectives To investigate the association between alcohol consumption and left ventricular (LV) function in a population with low average alcohol intake. Design, setting and participants A total of 1296 healthy participants, free from cardiovascular diseases, were randomly selected from the third wave of the Norwegian HUNT study (2006–2008) and underwent echocardiography. After validation of the inclusion criteria, 30 participants were excluded due to arrhythmias or myocardial or valvular pathology. Alcohol consumption, sociodemographic and major cardiovascular risk factors were assessed by questionnaires and clinical examination in the HUNT3. General linear models were used to analyse the cross-sectional associations between alcohol intake and LV indices. Primary and secondary outcome measures LV functional and structural indices were measured with tissue Doppler and speckle tracking echocardiography. Results We observed no associations between alcohol consumption and multivariable-adjusted LV functional indices. Excluding abstainers who reported regular alcohol consumption 10 years prior to the baseline did not change the results. Alcohol consumption was positively associated with LV mass indices (p |
Databáze: | OpenAIRE |
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