Investigation of Three Newly Identified Equine Parvoviruses in Blood and Nasal Fluid Samples of Clinically Healthy Horses and Horses with Acute Onset of Respiratory Disease
Autor: | Nicola Pusterla, Eric Delwart, Samantha Barnum, Kaitlyn E. James |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Environmental Science and Management
Veterinary medicine viruses Article Virus Acute onset Animal Production blood SF600-1100 medicine equine parvoviruses Respiratory system Lung equine copivirus healthy horses Nasal fluid Hepatitis General Veterinary biology Parvovirus business.industry equine parvovirus CSF Respiratory disease nasal fluid virus diseases equine parvovirus hepatitis biology.organism_classification medicine.disease Respiratory pathogens qPCR Infectious Diseases Emerging Infectious Diseases Good Health and Well Being QL1-991 Immunology Animal Science and Zoology business Infection Zoology sick equids |
Zdroj: | Animals Volume 11 Issue 10 Animals : an open access journal from MDPI, vol 11, iss 10 Animals, Vol 11, Iss 3006, p 3006 (2021) Animals : an Open Access Journal from MDPI |
ISSN: | 2076-2615 |
DOI: | 10.3390/ani11103006 |
Popis: | Three newly identified equine parvoviruses (equine parvovirus hepatitis (EqPV-H), equine parvovirus CSF (EqPV-CSF) and equine copivirus (Eqcopivirus)) have recently been discovered in horses with respiratory signs. However, the clinical impact of these three equine parvoviruses has yet to be determined. Nasal fluid samples and blood from 667 equids with acute onset of fever and respiratory signs submitted to a diagnostic laboratory were analyzed for the presence of common equine respiratory pathogens (equine influenza virus, equine herpesvirus-1/-4, equine rhinitis A and B virus, S. equi subspecies equi) as well as EqPV-H, EqPV-CSF and Eqcopivirus by qPCR. An additional 87 clinically healthy horses served as controls. One hundred and seventeen sick horses tested qPCR-positive for at least one of the three parvoviruses. Co-infections with common respiratory pathogens and parvoviruses were seen in 39 sick equids. All 87 clinically healthy horses tested qPCR-negative for all tested common respiratory pathogens and 10 healthy horses tested qPCR-positive for one of the equine parvoviruses. When the frequency of detection for EqPV-H, EqPV-CSF and Eqcopivirus of equids with respiratory signs was compared to that of clinically healthy horses, the difference was not statistically significant (p > 0.05), suggesting that the three recently identified equine parvoviruses do not contribute to the clinical picture of equids with respiratory disease. |
Databáze: | OpenAIRE |
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