Cutpoints for Muscle Mass and Strength Derived from Weakness or Mobility Impairment and Compared with Other Diagnostic Criteria in Community-Dwelling Elderly People
| Autor: | Jing-Min Liu, Ji-peng Shi, Xiu-Yuan Zheng, Jia-Qi Sun, Min Liu, Liao Tian, Yu Liu, Hong-qi Xu |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Cart Male Weakness medicine.medical_specialty Sarcopenia Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Logistic regression Muscle mass Body Mass Index 03 medical and health sciences 0302 clinical medicine Endocrinology Reference Values medicine Elderly people Humans Orthopedics and Sports Medicine Muscle Strength Mobility Limitation Muscle Skeletal Aged Muscle Weakness Receiver operating characteristic Hand Strength business.industry fungi medicine.disease Physical therapy Lean body mass Body Composition Female 030101 anatomy & morphology medicine.symptom business |
| Zdroj: | Calcified tissue international. 108(3) |
| ISSN: | 1432-0827 |
| Popis: | We identified the strength cutpoints concerning mobility impairment, then identified the muscle mass cutpoints concerning weakness, and compared the results with other diagnostic criteria to develop the clinical diagnostic criteria associated with functional impairment. In 7583 elderly people, classification and regression tree (CART) and receiver operating characteristic curve (ROC) analyses were used for determining cutpoints for handgrip strength (HGS) and appendicular lean mass (ALM) indices associated with slowness or weakness. Logistic regressions were then used to quantify the strength of the association between muscle mass (or strength) categories and weakness (or slowness). The CART second cutpoints of muscle mass and strength indices were lower than those specified by the ROC method and were between those cutpoints determined by the 20th and Mean-2SD methods. After adjusting for covariates, the associations remained significant in handgrip strength categories defined by the CART and ROC cutpoints and HGS/BMI categories defined by the CART, ROC, and 20th cutpoints in men and women (P |
| Databáze: | OpenAIRE |
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