Trousseau's syndrome due to asymptomatic pancreatic adenocarcinoma
Autor: | João Freire, Helena Damásio, Pedro Guedes, António Figueiredo, Gizela Rocha, Ana Serrano, Fernando Cunha, António Murinello, Liliana Alves |
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Rok vydání: | 2013 |
Předmět: |
medicine.medical_specialty
Heparina Adenocarcinoma pancreático Asymptomatic Gastroenterology Occult malignancy Internal medicine medicine Tromboflebite migratória Migratory thrombophlebitis Trousseau's syndrome Heparin business.industry Tromboflebite Síndrome de Trousseau medicine.disease Neoplasias Surgery Adenocarcinoma medicine.symptom business Pancreatic adenocarcinoma Neoplasia maligna oculta Adenocarcinoma Pancreático |
Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP |
ISSN: | 0872-8178 |
Popis: | The authors report a case of Trousseau's syndrome presenting in a previously asymptomatic 58-year-old man diagnosed with pancreatic adenocarcinoma and liver metastases during a workup prompted by migratory venous thrombosis and pulmonary embolism. It was followed by an ischaemic stroke that occurred while the patient was just one day off anticoagulant therapy with low-molecular-weight heparin to allow for liver and pancreatic biopsies. Trousseau's syndrome is defined by recurrent or migratory venous thrombosis, arterial embolism caused by non-bacterial thrombotic endocarditis, or both, in patients with underlying malignancy. Treatment relies on the lifelong administration of heparin, and its interruption – however brief – may promote new thrombotic events. |
Databáze: | OpenAIRE |
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