Right atrial function and prognosis in idiopathic pulmonary arterial hypertension
| Autor: | Maria Giovanna Russo, Berardo Sarubbi, Emanuele Romeo, Michele D'Alto, Antonello D'Andrea, Giovanni Di Salvo, Giovanni Maria Di Marco, Giancarlo Scognamiglio, Agostino Mattera Iacono, Paola Argiento, Eduardo Bossone |
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| Přispěvatelé: | D'Alto, M, D'Andrea, A, Di Salvo, G, Scognamiglio, G, Argiento, P, Romeo, E, Di Marco, Gm, Iacono, Am, Bossone, E, Sarubbi, B, Russo, Mg, D'Alto, Michele, D'Andrea, Antonello, DI SALVO, Giovanni, Scognamiglio, Giancarlo, Argiento, Paola, Romeo, Emanuele, Di Marco, Giovanni Maria, Mattera Iacono, Agostino, Bossone, Eduardo, Sarubbi, Berardo, Russo, Maria Giovanna |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Cardiac output Prognosi Hypertension Pulmonary Cardiac index Atrial Function Right 030204 cardiovascular system & hematology Doppler echocardiography Pulmonary arterial hypertension 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Prospective Studies Echocardiography Prognosis Right atrium Aged Female Follow-Up Studies Middle Aged Pulmonary wedge pressure medicine.diagnostic_test business.industry Hazard ratio Central venous pressure Pulmonary Atrial Function medicine.disease Pulmonary hypertension Right medicine.anatomical_structure Hypertension Vascular resistance Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | International journal of cardiology. 248 |
| ISSN: | 1874-1754 |
| Popis: | Aim: To determine whether right atrial (RA) function has prognostic value in patients with idiopathic pulmonary arterial hypertension (PAH).Methods and results: Overall, 104 patients (70 female, mean age 58 +/- 13 years) with idiopathic PAH underwent standard Doppler echocardiography and strain and strain rate (SR) analysis before right heart catheterization. At a mean follow-up of 22 +/- 7 months, 30 patients (29%) had clinical worsening. On Cox multivariable proportional-hazards regression analysis, RA reservoir function measured as peak longitudinal SR (hazard ratio [HR] 0.5; P < 0.0001), RA area (HR 1.2; P < 0.01), right ventricular (RV) SR (HR 0.6; P < 0.0001), cardiac index (HR 0.79; P < 0.01), and mixed venous oxygen saturation (HR 0.82; P < 0.01) were found to be independent correlates of cardiac events. A RA SR reservoir cut-off value of |
| Databáze: | OpenAIRE |
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