Antimicrobial photodynamic effect to treat residual pockets in periodontal patients: a randomized controlled clinical trial
| Autor: | Giorgio De Micheli, Marina Clemente Conde, Cláudio Mendes Pannuti, Priscila Vivas da Cruz Andrade, Verônica Franco de Carvalho, Rosario Dominguez Crespo Hirata, Mario Hiroyuki Hirata, Michelle De Franco Rodrigues |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Gingival and periodontal pocket Bleeding on probing Dental Plaque Gingiva Dentistry Dental plaque Aggregatibacter actinomycetemcomitans Periodontal Attachment Loss medicine Bacteroides Humans Periodontal Pocket Tannerella forsythia Low-Level Light Therapy Aged Pain Measurement Photosensitizing Agents biology business.industry Dental Plaque Index Middle Aged biology.organism_classification medicine.disease Chronic periodontitis Bacterial Load Methylene Blue Clinical trial Treatment Outcome Photochemotherapy Clinical attachment loss Chronic Periodontitis Periodontics Female Lasers Semiconductor Periodontal Index medicine.symptom business Porphyromonas gingivalis Treponema denticola Follow-Up Studies |
| Zdroj: | Journal of Clinical Periodontology. 42:440-447 |
| ISSN: | 0303-6979 |
| DOI: | 10.1111/jcpe.12393 |
| Popis: | Aim A randomized controlled clinical trial was designed to evaluate the efficacy of the photodynamic therapy (PDT) in the treatment of residual pockets of chronic periodontitis patients. Material and methods Thirty-four patients with at least four residual periodontal pockets undergoing maintenance care were included and randomly assigned to test group (PDT, n = 18) or control group (sham procedure, n = 16). The intervention was performed at baseline, 3, 6 and 12 months. Clinical parameters such as pocket probing depth (PPD), clinical attachment level (CAL), bleeding on probing (BoP) and plaque index (PI) were measured before intervention and after 3, 6 and 12 months. Subgingival samples were obtained at baseline, and after 7 days, 3, 6 and 12 months to quantify Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia by real-time polimerase chain reaction (PCR). Results All clinical variables showed significant improvement during the study, but there was no significant difference between test and control groups. The microbiological analyses showed no differences between groups at any time during the study. Conclusion Within the limits of this clinical trial and considering the laser and photosensitizer protocol used, PDT failed to demonstrate additional clinical and bacteriological benefits in residual pockets treatment. |
| Databáze: | OpenAIRE |
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