Multivariate Analysis of Influence of Vitamin Intake on Vascular Function Parameters by Sex in the General Spanish Population: EVA Study
| Autor: | María-Carmen Patino-Alonso, Gómez Sánchez M, Gómez Sánchez L, Manuel A. Gómez-Marcos, García ortiz L, Sánchez Salgado B, Natalia Sánchez-Aguadero, Rodríguez Sánchez E, Rosario Alonso-Domínguez |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Vitamin
Adult Male Multivariate analysis vitamins intake Population Physiology lcsh:TX341-641 030204 cardiovascular system & hematology Pulse Wave Analysis general population Article vascular function 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Vascular Stiffness canonical correspondence analysis Vitamin D and neurology Medicine Humans Ankle Brachial Index 030212 general & internal medicine education Pulse wave velocity Aged education.field_of_study Sex Characteristics Nutrition and Dietetics business.industry Retinol Age Factors Regression analysis Vitamins Middle Aged Reference Standards Diet chemistry Dietary Reference Intake Spain Multivariate Analysis Blood Vessels Female business lcsh:Nutrition. Foods and food supply Food Science |
| Zdroj: | Nutrients, Vol 12, Iss 3, p 643 (2020) Nutrients Volume 12 Issue 3 |
| ISSN: | 2072-6643 |
| Popis: | The influence of vitamin intake on vascular function parameters in the Spanish general population has not been studied. The main objective of this study is to analyze the influence of vitamin intake on vascular function and as a secondary objective the adequacy of vitamin intake in a sample of the Spanish population without previous cardiovascular disease and analyze the differences according to sex. Methods: We included 501 individuals obtained by simple random sampling with replacement (reference population 43,946). The average age was 55.90 ± 14.24 years, 49.70% men. Participants recorded the intake of vitamins using the EVIDENT app, previously validated, during a period of 3 days. Vascular function was assessed by measuring carotid-femoral pulse wave velocity (cfPWV) with the SphygmoCor device, cardio-ankle vascular index (CAVI) with the VaSera device and brachial-ankle pulse wave velocity (baPWV) by using a validated equation. Results: The vitamins with the least adequate intake was vitamin D, less than 5%, and vitamin B9, less than 35%. Vitamins with an adequate intake percentage, close to 100%, were B12 and B6. The multiple regression analysis showed a negative association between cfPWV and vitamin B2 in both sexes, and a positive one with retinol in men and B3 in women. baPWV was negatively associated with vitamins B1 and B12 in women and B9 in men, while being positively linked with B6 in men. CAVI presented a negative association with vitamin D in women. The results were similar in the canonical correspondence analysis. In conclusion, the results of this study suggest that the influence of vitamins on vascular function is not homogeneous and varies according to the parameter analyzed. Thus, in men, vitamins B2 and retinol were associated with cfPWV and vitamins B6 and B9 with baPWV. In women, vitamins B2 and B3 were related cfPWV, vitamins B1 and B12 with cfPWV and vitamin D with CAVI. |
| Databáze: | OpenAIRE |
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