The comparison of the pathological data of oropharyngeal masses between HIV and non-HIV patients

Autor:	Jideofor Alex-Okoro, FT Orji, James O. Akpeh, Nnaemeka G. Umedum
Rok vydání:	2016
Předmět:	Adult Male Oncology medicine.medical_specialty Adolescent Oropharynx HIV Infections Malignancy Lymphoid hyperplasia Young Adult 03 medical and health sciences 0302 clinical medicine Pseudolymphoma Acquired immunodeficiency syndrome (AIDS) Cervical lymphadenopathy hemic and lymphatic diseases Internal medicine medicine Humans Young adult Child 030223 otorhinolaryngology Aged Retrospective Studies Aged 80 and over business.industry Lymphoma Non-Hodgkin virus diseases Retrospective cohort study General Medicine Middle Aged medicine.disease Hodgkin Disease Lymphoma Oropharyngeal Neoplasms Oropharyngeal Neoplasm Otorhinolaryngology 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female medicine.symptom business
Zdroj:	Acta Oto-Laryngologica. 136:969-972
ISSN:	1651-2251 0001-6489
DOI:	10.3109/00016489.2016.1170878
Popis:	Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid hyperplasia in HIV patients.The aim of this study was to compare the histology of oropharyngeal masses between HIV positive and negative patients.A retrospective review of 119 patients who underwent oropharyngeal biopsies in a tertiary institution between 2007-2014 and whose HIV status was known (HIV positives =47; negatives =72).Malignancies occurred in 63.8% of HIV patients and 65% of the negative group (p = 0.87). While non-Hodgkin's lymphoma (NHL), squamous cell carcinoma (SCC), and Hodgkin's lymphoma (HL) constituted 40%, 27%, and 17% of malignancies in HIV patients, respectively; in the HIV-negative group, it was 53%, 13%, and 2% for SCC, NHL, and HL, respectively (p = 0.039, 0.017, and 0.035, respectively). Reactive lymphoid proliferation accounted for 82.4% of the benign masses in the HIV positive group. Malignant tumours were recorded more in younger patient in the HIV positive than the negative group (p = 0.001).
Databáze:	OpenAIRE
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