The role of central and peripheral μ- and δ-opiate receptors in mediating the antiarrhythmic effect of adaptation

Autor:	A. V. Krylatov, Yu. B. Lishmanov, Leonid N. Maslov, E. V. Uskina
Rok vydání:	1996
Předmět:	medicine.medical_specialty Chemistry Antagonist General Medicine (+)-Naloxone Pharmacology Methylnaltrexone General Biochemistry Genetics and Molecular Biology Peripheral Endocrinology Naltrindole Opiate receptors Internal medicine medicine Antiarrhythmic effect Adaptation medicine.drug
Zdroj:	Scopus-Elsevier
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02447012
Popis:	Adaptation prevents epinephrine-induced arrhythmias in rats, the effect being abolished by naloxone, a μ-receptor antagonist, but not by the δ-receptor antagonist naltrindole. Methylnaltrexone, a blocker of peripheral μ-receptors, weakens the effect of adaptation without eliminating it completely. Central and peripheral μ-receptors may play a key role in the antiarrhythmic effect of adaptation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce46e796349d554a85d9995701b1736 https://doi.org/10.1007/bf02447012 Zobrazit plný text záznamu Full text from SpringerLink