Automation of the Magos Mercury Determination
| Autor: | Jean-Pierre Farant, Donald C. Wigfield, Sherry L. Perkins, Jeffrey E. Willette, Judy E. MacKeen |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Autoanalysis
Chemical Health and Safety Materials science business.industry Health Toxicology and Mutagenesis Water jet chemistry.chemical_element Schematic Mercury Toxicology Automation Analytical Chemistry Mercury (element) Tray chemistry Reagent Humans Environmental Chemistry Timer business Process engineering Oxidation-Reduction Hair Mercury analysis |
| Zdroj: | Journal of Analytical Toxicology. 6:276-278 |
| ISSN: | 1945-2403 0146-4760 |
| DOI: | 10.1093/jat/6.6.276 |
| Popis: | Recent communications from these laboratories (1,2) have reported modified procedures, smaller reaction vessels and reagent volumes, and elimination of the matrix effect, in the Magos method of mercury analysis. With these developments completed, automation of the method (i.e., operator involvement only every 50 or 100 samples) may be considered. Such a development is becoming crucially necessary in view of the increasing number of human hair and blood samples requiring mercury analysis, especially from native populations in Canada (3). This paper reports accomplishment of this objective and describes in detail an apparatus for this purpose. ly, the addition of a water jet for rinsing the apparatus between samples, coupled with a drain at the bottom of the reaction vessel, removed the need for apparatus disassembly. Thirdly, the incorporation of signal integration eliminated the matrix effect (2) and thus, not only removed the need for timeconsuming additional control determinations to measure the extent of this effect, but also greatly simplified the subsequent data processing. Finally, automatic loading of the samples on the one-by-one sample dispenser completely removed the need for an operator from the sample-to-sample routine. Thus, operator control is required only for the initial sample preparation and loading, apparatus (tart-up, and final examination of recorded data. In order to achieve the above, a 10-channel electronic timer was sufficient to control all operations, coupled with solenoid valves to control the reagent addition, sample addition, and rinse cycle. A record-player type arm was required to deliver the sample from the sample tray to the reaction vessel. The details and schematic diagrams of the apparatus are given in the Experimental section. It should be noted that the apparatus is not limited to mercury analysis, but could be readily adapted to other routine analyses, such as fluoride analysis in urine using an ionselective electrode, and creatinine analysis by coupling to a spectrophotometer. |
| Databáze: | OpenAIRE |
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