The influence of diet and probiotics on the response of solid tumours to immunotherapy: Present and future perspectives
| Autor: | Luis Figuero-Pérez, David León-Jiménez, Juan J. Cruz-Hernández, Alejandro Olivares-Hernández, Jose Pablo Miramontes-Gonzalez, Rogelio González-Sarmiento |
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| Přispěvatelé: | [Olivares-Hernandez, Alejandro] Univ Hosp Salamanca, Dept Med Oncol, Salamanca 37007, Spain, [Figuero-Perez, Luis] Univ Hosp Salamanca, Dept Med Oncol, Salamanca 37007, Spain, [Jesus Cruz-Hernandez, Juan] Univ Hosp Salamanca, Dept Med Oncol, Salamanca 37007, Spain, [Olivares-Hernandez, Alejandro] Inst Biomed Res Salamanca IBSAL, Salamanca 37007, Spain, [Figuero-Perez, Luis] Inst Biomed Res Salamanca IBSAL, Salamanca 37007, Spain, [Gonzalez-Sarmiento, Rogelio] Inst Biomed Res Salamanca IBSAL, Salamanca 37007, Spain, [Jesus Cruz-Hernandez, Juan] Inst Biomed Res Salamanca IBSAL, Salamanca 37007, Spain, [Leon-Jimenez, David] Hosp Virgen del Rocio, Dept Internal Med, Seville 41013, Spain, [Pablo Miramontes-Gonzalez, Jose] Univ Hosp Rio Hortega, Dept Internal Med, Valladolid 47012, Spain, [Pablo Miramontes-Gonzalez, Jose] Univ Valladolid, Dept Med, Valladolid 45005, Spain |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Target
Technology Cancer Research Colorectal-cancer medicine.medical_treatment Immune checkpoint inhibitors Antibiotics 3205 Medicina Interna Gut flora Oncología Medicina Interna General Materials Science Biology (General) Instrumentation solid tumours Fluid Flow and Transfer Processes biology Physics General Engineering Vegan Diet Engineering (General). Civil engineering (General) Computer Science Applications Chemistry 3201.01 Oncología Tumores sólidos Red meat Dieta immunotherapy Immunotherapy TA1-2040 medicine.drug_class QH301-705.5 QC1-999 Immunology Gut microbiota Immune system medicine Microbiome Obesity Fiber Inmunoterapia QD1-999 Solid tumours business.industry Process Chemistry and Technology Probiotics Probióticos biology.organism_classification Diet probiotics Ctla-4 business diet |
| Zdroj: | Applied Sciences, Vol 11, Iss 8445, p 8445 (2021) |
| Popis: | Producción Científica Currently, various immunotherapeutic treatments are revolutionizing therapies that treat solid neoplasms. For these treatments, within immunotherapy, immune checkpoint inhibitors (ICIs) are the most widely used drugs. Diverse studies have shown the influence of diet and probiotics on the response to ICIs and consequently on the survival rates associated with different neoplasms. The use of various antibiotics, probiotics, and prebiotics has been associated with changes in the gut microbiota, and this, in turn, with resistance to immunotherapy. Together with the above, a lower intake of red meat and greater consumption of a Mediterranean, vegetarian, or vegan diet have led to a new way of understanding the mechanisms of resistance to ICIs. Omega-3 and polyphenol supplements are also powerful regulators of the microbiome whose influence on the immune system. Therefore, this review covers the influence of diet and probiotics on the response to immunotherapy in patients who have solid tumours. |
| Databáze: | OpenAIRE |
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