| Autor: |
Anja van Biezen, Linda Koster, Simona Iacobelli, Hareth Nahi, Xavier Leleu, Nico Gagelmann, Diderik-Jan Eikema, Nicolaus Kröger, Anne-Marie Stoppa, Denis Caillot, Miklós Udvardy, Charles Crawley, Maija Itälä-Remes, Tamas Masszi, Stig Lenhoff, Ann Hunter, Laurent Garderet, Pietro Pioltelli, Clara Mariette, Martin R. Schipperus, Maurizio Musso, Michel Delforge, John A. Snowden, William Arcese |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Haematologica, 103(5), 890-897
Haematologica |
| Popis: |
We investigated extramedullary disease in newly diagnosed multiple myeloma patients and its impact on outcome following first-line autologous stem cell transplantation. We identified 3744 adult myeloma patients who received up-front single (n=3391) or tandem transplantation (n=353) between 2005 and 2014 with available data on extramedullary involvement at diagnosis. The overall incidence of extramedullary disease was 18.2% (n=682) and increased per year from 6.5% (2005) to 23.7% (2014). Paraskeletal involvement was found in 543 (14.5%) and extramedullary organ involvement in 139 (3.7%). More patients with extramedullary organ involvement had multiple involved sites (≥2; P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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