Association Between Psoriasis with Arthritis and Hearing Impairment in US Adults: Data from the National Health and Nutrition Examination Survey
Autor: | Bernard A. Cohen, Shawn G Kwatra, Yevgeniy R. Semenov, Esther Y. Hsiang, Xuan Hui, Amy H Huang, Milan J. Anadkat, C. Herbosa |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male medicine.medical_specialty National Health and Nutrition Examination Survey Hearing loss Immunology Population Arthritis Comorbidity 030207 dermatology & venereal diseases 03 medical and health sciences Psoriatic arthritis 0302 clinical medicine Rheumatology Psoriasis Internal medicine Prevalence medicine Humans Immunology and Allergy Hearing Loss education Depression (differential diagnoses) 030203 arthritis & rheumatology education.field_of_study business.industry Arthritis Psoriatic Middle Aged Nutrition Surveys medicine.disease Mental health United States Cross-Sectional Studies Logistic Models Female medicine.symptom business |
Zdroj: | The Journal of Rheumatology. 46:587-594 |
ISSN: | 1499-2752 0315-162X |
Popis: | Objective.Emerging data has linked inflammatory arthritis with hearing impairment (HI). The objective of this study was to investigate the relationship between psoriasis with arthritis (PsA) and HI in the US population. Given the known association of HI and depression, a secondary aim is to investigate the effect of PsA on mental well-being.Methods.Cross-sectional study using the National Health and Nutrition Examination Survey for adults aged ≥ 20 years (n = 10,747). Association of PsA with above outcomes was examined using multivariable generalized linear and ordinal logistic regression models, adjusted for demographics and medical comorbidities. Structural equation models examined the extent to which HI mediated the effect of PsA on mental health.Results.Individuals with PsA were more likely to report hearing difficulties (OR 1.50, p = 0.043), visit a mental health provider (OR 1.62, p = 0.084), have 1.62 more days of poor mental health over the previous month (p = 0.033), and have depression (OR 2.01, p = 0.015) compared to controls. HI mediated 6.5%, 8.3%, and 5.0% of the effect of PsA on the above mental health outcomes, respectively.Conclusion.PsA is independently associated with a significantly increased risk of HI, which partially mediates an association with worsened psychiatric outcomes. |
Databáze: | OpenAIRE |
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