Dopamine D2 receptor TaqIA and TaqIB polymorphisms in Parkinson's disease

Autor:	Yanni Tan, Sau-Ying Lum, A. Chai, C. Tan, Meng-Cheong Wong, M.L. Teoh, Stephanie M.C. Fook-Cheong, Y. Yih, Hui Shen, Eng-King Tan, Y. Zhao
Rok vydání:	2003
Předmět:	Genetic Markers Male Linkage disequilibrium medicine.medical_specialty Parkinson's disease Genotype Linkage Disequilibrium Central nervous system disease Degenerative disease Gene Frequency Dopamine receptor D2 Internal medicine medicine Humans Genetic Predisposition to Disease Taq Polymerase Alleles DNA Primers Genetics Analysis of Variance Polymorphism Genetic Receptors Dopamine D2 business.industry Case-control study Parkinson Disease Middle Aged medicine.disease Endocrinology Neurology Female Neurology (clinical) business
Zdroj:	Movement Disorders. 18:593-595
ISSN:	1531-8257 0885-3185
DOI:	10.1002/mds.10406
Popis:	In a case control study, we examined the association of DRD2 Taq1A and Taq1B polymorphisms and risk of PD, and evaluated the strength of linkage disequilibrium of the polymorphisms. The Taq1A and Taq1B polymorphisms were in strong linkage disequilibrium. There was, however, no significant association of the two polymorphisms with PD. © 2003 Movement Disorder Society
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd5b411ee7901ea9752f899e54cf5f1 https://doi.org/10.1002/mds.10406 Zobrazit plný text záznamu Plný text