Mapping of polycrystalline films of biological fluids utilizing the Jones-matrix formalism
| Autor: | Leonid Y. Pidkamin, Alexander Bykov, V. A. Ushenko, Alexander G. Ushenko, Michael Yu Sakchnovsky, Alexander V. Dubolazov, Igor Meglinski, Anna B. Bodnar, Yuriy A. Ushenko |
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| Rok vydání: | 2018 |
| Předmět: |
поляриметрическая визуализация
Materials science Condensed matter physics Physics::Optics 02 engineering and technology оптическая анизотропия 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences Industrial and Manufacturing Engineering Atomic and Molecular Physics and Optics поликристаллические пленки 010309 optics Condensed Matter::Materials Science биологические жидкости 0103 physical sciences Biological fluids Джонса матрицы Crystallite 0210 nano-technology Instrumentation Matrix formalism |
| Zdroj: | Laser physics. 2018. Vol. 28. P. 025602 (1-6) |
| ISSN: | 1555-6611 1054-660X |
| Popis: | Utilizing a polarized light approach, we reconstruct the spatial distribution of birefringence and optical activity in polycrystalline films of biological fluids. The Jones-matrix formalism is used for an accessible quantitative description of these types of optical anisotropy. We demonstrate that differentiation of polycrystalline films of biological fluids can be performed based on a statistical analysis of the distribution of rotation angles and phase shifts associated with the optical activity and birefringence, respectively. Finally, practical operational characteristics, such as sensitivity, specificity and accuracy of the Jones-matrix reconstruction of optical anisotropy, were identified with special emphasis on biomedical application, specifically for differentiation of bile films taken from healthy donors and from patients with cholelithiasis. |
| Databáze: | OpenAIRE |
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