[3H]Prostaglandin accumulation in vitro by baboon uterus
Autor: | M. J. K. Harper, T. J. Kuehl, M. A. Jones |
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Rok vydání: | 1985 |
Předmět: |
medicine.medical_specialty
Time Factors Endocrinology Diabetes and Metabolism media_common.quotation_subject Uterus Alpha (ethology) Prostaglandin Dinoprost Dinoprostone Incubation period chemistry.chemical_compound Organ Culture Techniques Endocrinology biology.animal Internal medicine medicine Animals Fallopian Tubes Menstrual Cycle Menstrual cycle media_common biology urogenital system Chemistry Prostaglandins E Prostaglandins F Significant difference In vitro medicine.anatomical_structure embryonic structures Female Rabbits Papio Baboon |
Zdroj: | Journal of Endocrinology. 106:49-53 |
ISSN: | 1479-6805 0022-0795 |
DOI: | 10.1677/joe.0.1060049 |
Popis: | Uteri from mature baboons at various stages of the menstrual cycle were collected at autopsy. Transverse slices of the uteri were incubated with [3H]prostaglandins in Tyrode's buffer. Bound and free ligands were separated by filtration. Prostaglandin (PG) accumulation by the tissue slices was evaluated as a function of incubation time, PG type and concentration, temperature, wet weight of tissue and stage of the menstrual cycle. There was no significant difference in PG accumulation in response to PG type (PGE2 or PGF2α) or stage of the menstrual cycle. These results from baboon uteri were compared with those using baboon oviducts and also rabbit uteri and oviducts. Unlike the rabbit tissues, the baboon oviducts and uterine tissues did not exhibit specific net accumulation of prostaglandins. J. Endocr. (1985) 106, 49–53 |
Databáze: | OpenAIRE |
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