Ultrasound assessment of diaphragm function in patients with late-onset Pompe disease

Autor:	Gaetano Caramori, Michele Gaeta, Olimpia Musumeci, Antonio Toscano, Lucia Monaco, Graziana Tavilla, Paolo Ruggeri
Rok vydání:	2020
Předmět:	Spirometry medicine.medical_specialty Vital capacity Supine position Diaphragm Vital Capacity Dermatology 03 medical and health sciences FEV1/FVC ratio Respiratory muscle strength 0302 clinical medicine Functional residual capacity Internal medicine Humans Medicine Respiratory function Lung volumes 030212 general & internal medicine Ultrasonography medicine.diagnostic_test Glycogen Storage Disease Type II business.industry General Medicine Lung function Diaphragm (structural system) Psychiatry and Mental health Late-onset Pompe disease Cardiology Female Neurology (clinical) business 030217 neurology & neurosurgery
Zdroj:	Neurological Sciences. 41:2175-2184
ISSN:	1590-3478 1590-1874
DOI:	10.1007/s10072-020-04316-6
Popis:	Late-Onset Pompe Disease (LOPD) is characterized by progressive limb-girdle muscle weakness and respiratory dysfunction. Diaphragm is the most impaired muscle in LOPD and its dysfunction cause major respiratory symptoms. The aim of this study was to evaluate the correlation between diaphragm thickness and mobility assessed by ultrasonography and respiratory function and muscle strength tests in patients with LOPD. 17 patients with LOPD (9 female, 47 ± 15 years) and 17 age and gender-matched healthy controls underwent spirometry, muscle strength testing, and ultrasound evaluation of diaphragm excursion and thickness. The following parameters were significantly reduced in LOPD patients versus controls (all p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc7e5ee3f93244db1741993a99841a2 https://doi.org/10.1007/s10072-020-04316-6 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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