The value of transcranial Doppler sonography in the differential diagnosis of Alzheimer disease vs multi-infarct dementia
| Autor: | Stefan Biedert, Hans Förstl, Walter Hewer |
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| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Pathology Cerebral arteries Blood Pressure Diagnosis Differential Degenerative disease Alzheimer Disease Internal medicine medicine.artery medicine Basilar artery Humans Dementia Ultrasonics Molecular Biology Aged Cerebral infarction business.industry General Neuroscience Cerebral Arteries Intracranial Embolism and Thrombosis Middle Aged medicine.disease Echoencephalography Transcranial Doppler Dementia Multi-Infarct medicine.anatomical_structure Basilar Artery Cerebrovascular Circulation cardiovascular system Vascular resistance Cardiology Female Vascular Resistance Neurology (clinical) Alzheimer's disease business |
| Zdroj: | Molecular and Chemical Neuropathology. 19:15-23 |
| ISSN: | 1044-7393 |
| DOI: | 10.1007/bf03160165 |
| Popis: | Primary degenerative dementia of the Alzheimer type and multi-infarct dementia exhibit differences in cerebrovascular blood flow velocity profiles, which were investigated by means of transcranial Doppler sonography. The pulsatility indices, as angle-independent parameters of peripheral vascular resistance, measured in middle cerebral and basilar arteries of patients with multi-infarct dementia (MID), were significantly increased (p < 0.005) with respect to cases of primary degenerative dementia of the Alzheimer type and to healthy age-matched controls. Approximately 75% of all MID patients exhibited small vessel disease rather than thromboembolism from the extracranial arteries and the heart, as judged by extracranial and transcranial Doppler sonographies, computerized cerebral tomographies, EEGs, and, if necessary, 2-D echocardiographies. |
| Databáze: | OpenAIRE |
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